Yoshinobu Matsuo

Dissociation of Bax from a Bcl-2/Bax Heterodimer Triggered by Phosphorylation of Serine 70 of Bcl-2 (2001)

Shitashige, Miki, Toi, Masakazu, Yano, Takeo, Shibata, Masao, Matsuo, Yoshinobu, Shibasaki, Futoshi

Serine 70 in the loop region of Bcl-2 is specifically phosphorylated by paclitaxel-treat-ment in tumor cells and BHK cells expressing Bcl-2. The phosphorylation of serine 70 of Bcl-2 (pS70-Bcl-2)...

Recombination hotspot associated factors specifically recognize novel target sequences at the site of interchromosomal rearrangements in T-ALL patients with t(8;14)(q24;q11) and t(1;14)(p32;q11) (1994)

Kasai, Masataka, Aokl, Katsunori, Matsuo, Yoshinobu, Minowada, Jun, Maziarz, Richard T., Strominger, Jack L.

A DNA binding protein was identified which binds to two novel target-like sequences: (I) at the 5′ flanking site of the breakpoint junction of chromosome 8 in a patient with T-acute lymphoblastlc...

Deficiency of BLNK hampers PLC-γ2 phosphorylation and Ca2+ influx induced by the pre-B-cell receptor in human pre-B cells

Taguchi, Tomoko, Kiyokawa, Nobutaka, Takenouch, Hisami, Matsui, Jun, Tang, Wei-Ran, Nakajima, Hideki, ...

B-cell linker protein (BLNK) is a component of the B-cell receptor (BCR) as well as of the pre-BCR signalling pathway, and BLNK–/– mice have a block in B lymphopoiesis at the pro-B/pre-B cell...

Overexpression of PDZK1 within the 1q12-q22 Amplicon Is Likely To Be Associated with Drug-Resistance Phenotype in Multiple Myeloma

Inoue, Jun, Otsuki, Takemi, Hirasawa, Akira, Imoto, Issei, Matsuo, Yoshinobu, Shimizu, Shiroh, ...

We investigated DNA copy number aberrations in 37 cell lines derived from multiple myelomas (MMs) using comparative genomic hybridization, and 11 (29.7%) showed high-level gain indicative of gene...

Preferential Expansion of Vγ9-JγP/Vδ2-Jδ3 γδ T Cells in Nasal T-Cell Lymphoma and Chronic Active Epstein-Barr Virus Infection

Oyoshi, Michiko K., Nagata, Hiroshi, Kimura, Nobuhiro, Zhang, Yu, Demachi, Ayako, Hara, Toshiro, ...

We recently established an Epstein-Barr virus (EBV)-positive γδ T-cell line from a nasal T/natural killer (NK)-cell lymphoma (Nagata H, Konno A, Kimura N, Zhang Y, Kimura M, Demachi A, Sekine T,...