Yoshio Naomoto

Analysis of Fecal DNA Methylation to Detect Gastrointestinal Neoplasia (2009)

Nagasaka, Takeshi, Tanaka, Noriaki, Cullings, Harry M., Sun, Dong-Sheng, Sasamoto, Hiromi, Uchida, Takuyuki, ...

BackgroundThe development of noninvasive screening tests is important to reduce mortality from gastrointestinal neoplasia. We sought to develop such a test by analysis of DNA methylation from...

Synergistic Effect of Tumor Necrosis Factor-α and Interferon-α on the Induction of Apoptosis Detected by BM-I/JIMRO: A New Marker of Apoptosis (2007)

Zhang, Wei, Naomoto, Yoshio, Tanaka, Noriaki, Hizuta, Akio, Orita, Kunzo

The effects of the combination of natural human tumor necrosis factor-alpha (nHuTNF-alpha) and natural human interferon-alpha (nHuIFN-alpha) on the induction of apoptosis were investigated by...

Postoperative Gastric Motility, Secretory Function, and Pre- and Postoperative Carbohydrate Metabolic States in Esophageal Cancer Patients (2007)

Ishizuka, Shinji, Kamikawa, Yasuaki, Naomoto, Yoshio, Tanaka, Noriaki, Orita, Kunzo

This study was undertaken to assess postoperative gastric motility and gastric acid secretion, and pre- and postoperative carbohydrate metabolism in patients with esophageal cancer. The gastric...

Inhibition of Liver Regeneration in Mice Following Extended Hepatectomy by Transfusion of Lymphokine Activated Killer Cells (2007)

Tanaka, Noriaki, Tatemoto, Akihiko, Urabe, Takamitsu, Ono, Minoru, Hizuta, Akio, Naomoto, Yoshio, ...

Lymphokine activated killer (LAK) cells can destroy not only tumor cells but also syngeneic liver cells. In this study, the effects of passive transfer of LAK cells on liver regeneration were...

Antiproliferative effects of suramin on human cancer cells in vitro and in vivo. (2007)

Bai, Liyan, Naomoto, Yoshio, Miyazaki, Masahiro, Orita, Kunzo, Namba, Masayoshi

The present experiment was undertaken to study what types of human cancers are responsive to the antiproliferative effects of suramin. The human malignant cells used were as follows: cervical cancer...

The impact of triple drug immunosuppression on clinical results of cadaveric kidney transplantation: a comparison of conventional immunosuppression. (2007)

Sakagami, Kenichi, Saito, Shinya, Shiozaki, Shigehiro, Takasu, Shinji, Matsuno, Tsuyoshi, Fujiwara, Takuzo, ...

A retrospective study was carried out in 110 cadaveric kidney transplant recipients to compare the effects of low doses of cyclosporine (CsA), azathioprine (AZP) and steroids (triple-drug therapy)...

Antitumor effect of natural human tumor necrosis factor-alpha and natural human interferon-alpha in combination against human cancer transplanted into nude mice. (2007)

Naomoto, Yoshio, Tanaka, Noriaki, Orita, Kunzo

We studied the in vivo antitumor effects of natural human tumor necrosis factor-alpha (nHuTNF-alpha) and natural human interferon-alpha (nHuIFN-alpha), both of which were produced by HVJ...

Antitumor effect of combined intraperitoneal administration of human recombinant interferon-beta and interferon-gamma against intraabdominal carcinomatosis in nude mice. (2007)

Kondo, Hidenori, Tanaka, Noriaki, Naomoto, Yoshio, Orita, Kunzo

The development of useful therapy for intraabdominal carcinomatosis originating from gastrointestinal cancer is an important theme in cancer therapy. We developed recently an experimental model of...

Hepatic infarction following abdominal interventional procedures. (2006)

Fujiwara, Hiroyasu, Kanazawa, Susumu, Hiraki, Takao, Mimura, Hidefumi, Yasui, Kotaro, Akaki, Shiro, ...

To clarify the incidence, background, and progress of hepatic infarction following interventional procedures, cases of hepatic infarction following interventional procedures at our department during...

Retroperitoneal liposarcoma presenting a indirect inguinal hernia (2006)

Noguchi, Hirofumi, Naomoto, Yoshio, Haisa, Minoru, Yamatsuji, Tomoki, Shigemitsu, Kaori, Uetsuka, Hirokazu, ...

A 60-year-old man was admitted to our hospital with a right inguinal swelling that had been growing in size without any pain for 7 months. We diagnosed the growth as a right inguinal hernia and...

A Case of Advanced Esophageal Cancer with Extensive Lymph Node Metastases Successfully Treated with Multimodal Therapy (2002)

Shigemitsu, Kaori, Naomoto, Yoshio, Shirakawa, Yasuhiro, Haisa, Minou, Gunduz, Mehmet, Tanaka, Noriaki

Advanced esophageal cancer patients with extensive lymph node metastases show extremely poor prognosis and the long-term outcome is poorer with the involvement of more lymph nodes. We report here a...

Five Cases of Early Gastric Cancer in the Reconstructed Gastric Tube after Radical Resection for Esophageal Cancer (2002)

Shigemitsu, Kaori, Naomoto, Yoshio, Shirakawa, Yasuhiro, Haisa, Minoru, Gunduz, Mehmet, Tanaka, Noriaki

We report seven early gastric cancers in five patients, which arose in the reconstructed gastric tube after radical resection for esophageal cancer. Four of them occurred in the middle gastric tube...

Leiomyosarcoma Arising in a Remnant Esophagus After Esophagectomy: a Case Report (2001)

Nakao, Atsunori, Naomoto, Yoshio, Shigemitsu, Kaori, Shirakawa, Yasuhiro, Yamatsuji, Tomoki, Kataoka, Masafumi, ...

We report an extremely rare case of leiomyosarcoma arising from a remnant esophagus. A 52-year-old Japanese man was referred to our hospital for treatment of a tumor arising from the remnant...

A Family of Multiple Endocrine Neoplasia Type 2A with the RET Proto-oncogene Mutation in Codon 618 (Cys{->}Arg) (2001)

Nakao, Atsunori, Naomoto, Yoshio, Kataoka, Masafumi, Haisa, Minoru, Kataoka, Kazuhiko, Saitoh, Shinya, ...

Multiple endocrine neoplasia type 2 (MEN-2) is a hereditary syndrome characterized by medullary thyroid carcinoma (MTC), pheochromocytoma and hyperplasia or adenoma of the parathyroid gland with...

A Case of Thyroid Cancer Involving the Trachea: Treatment by Partial Tracheal Resection and Repair with a Latissimus Dorsi Musculocutaneous Flap (2000)

Shigemitsu, Kaori, Naomoto, Yoshio, Haisa, Minoru, Yamatsuji, Tomoki, Noguchi, Hirofumi, Kataoka, Masafumi, ...

A 65 year-old man had undergone left thyroidectomy for thyroid cancer. The cancer had directly invaded the cervical esophagus and trachea and the patient was referred to our hospital for radical...

In Vitro Induction of Perforin mRNA and Cytotoxic Activities in Human Splenocytes by the Streptococcal Preparation, OK-432 (1991)

Kataoka, Kazuhiko, Naomoto, Yoshio, Orita, Kunzo

Mononuclear cells were isolated from a spleen excised during surgery and cultured with 0.05 KE (Klinische Einheit)/ml of the streptococcal preparation, OK-432, or 700 JRU (Japan Reference...

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

Zhang, Lin, Volinia, Stefano, Bonome, Tomas, Calin, George Adrian, Greshock, Joel, Yang, Nuo, ...

MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that function as negative gene regulators. miRNA deregulation is involved in the initiation and progression of human cancer; however,...