Nikolaidis, Lazaros A, Sturzu, Anthony, Stolarski, Carol, Elahi, Dariush, Shen, You-Tang, Shannon, Richard P
Background: The failing heart demonstrates a preference for glucose as its metabolic substrate. Advanced, severe DCM is characterized by depletion of adenosine triphosphate (ATP) stores, which may be...
Nikolaidis, Lazaros A, Hentosz, Teresa, Doverspike, Aaron, Huerbin, Rhonda, Stolarski, Carol, Shen, You-Tang, ...
Objectives: To investigate the effect of α, β1 and β2 adrenergic receptor (AR) stimulation on coronary hemodynamics, myocardial oxygen consumption (MvO2) and metabolic substrate preference in...
Shen, You-Tang, Buie, Pamela S, Lynch, Joseph J, Krause, Stephen M, Ma, Xin-Liang
Background: Although it is known that endothelin (ET-1) is elevated in heart failure (HF), it remains unclear if chronic ETA/B receptor antagonism affects the progression of HF, particularly by...
Shen, You-Tang, Wiedmann, R.T., Greenland, B.D., Lynch, J.J., Grossman, W.
Objective: The goal of this study was to determine if the hemodynamic effects of the combined administration of an angiotensin converting enzyme (ACE) inhibitor and angiotensin II type 1 (AT1)...
Effects of anaesthesia and recent surgery on diastolic function (1994)
Ihara, Tadashi, Shannon, Richard P, Komamura, Kazuo, Pasipoularides, Ares, Patrick, Thomas, Shen, You-Tang, ...
Objective: The aims were to determine the effects and the extent to which halothane anaesthesia affects diastolic function both immediately after and remote from surgery and to investigate whether...
Lieber, Samuel C., Qiu, Hongyu, Chen, Li, Shen, You-Tang, Hong, Chull, Hunter, William C., ...
The objective of this study was to test the hypothesis that the mechanism mediating left ventricular (LV) dysfunction in the aging rat heart involves, in part, changes in cardiac cytoskeletal...