Yu Chen, Andreas Eisele, Christian Federmann, Eva Hasler, Michael Jellinghaus, Silke Theison
We describe an architecture that allows to combine statistical machine translation (SMT) with rule-based machine translation (RBMT) in a multi-engine setup. We use a variant of standard SMT...
Aref Agheli; Brookdale University Hospital Medical Center, Yelena Patsiornik; Maimonides Hospital Medical Center, Yu Chen; South Naussau Community Hospital, M. Rashid Chaudhry; Brookdale Hospital Medical Center, Jen Chin Wang; Brookdale University Hospital Medical Center
The prostate cancer is the most common malignancy and is the second most common cause of the cancer-associated mortality in males. Bone metastasis is frequent and leads to serious and costly...
Zhou, Bin, Rao, Li, Peng, Ying, Wang, Yanyun, Li, Yi, Gao, Linbo, ...
Abstract Background Previous studies in experimental and human heart failure showed that nuclear factor kappa B (NF-κB) is chronically activated in cardiac myocytes, suggesting an important...
Chen, Yu, Regnault, N., Ferreira, R., Zhu, Bang-Fen, Bastard, G.
We report a theoretical study of the carrier relaxation in a quantum cascade laser (QCL) subjected to a strong magnetic field. Both the alloy (GaInAs) disorder effects and the Frohlich interaction...
Drug Exposure Side Effects from Mining Pregnancy Data (2009)
Yu Chen, Lars Henning, Pedersen Wesley, W. Chu, Jorn Olsen
This paper presents an interdisciplinary collaborative research project between the Epidemiology Department and the Computer Science Department for using data mining technique to analyze data from...
BIOINFORMATICS ORIGINAL PAPER (2009)
Genome Analysis, Yu Chen, Dong Xu
Understanding protein dispensability through machine-learning analysis of high-throughput data
Agent-based Microsimulation of Economy from A Complexity Perspective (2009)
Yu Chen, Xiaomeng Su, Jinghai Rao, Hui Xiong
An often-noted feature of computational agents research is its interdisciplinary nature. The growing use of computational models in social, biological and economic systems raises many question and...
Magnetic Field Induced Superconductivity in Out-of-Equilibrium Nanowires (2009)
Chen, Yu, Snyder, S., Goldman, A. M.
Four-terminal resistance measurements have been carried out on Zn nanowires formed using electron-beam lithography. When driven resistive by current, these wires re-enter the superconducting state...
Arsenic and Cardiovascular Disease (2009)
States, J. Christopher, Srivastava, Sanjay, Chen, Yu, Barchowsky, Aaron
Chronic arsenic exposure is a worldwide health problem. Although arsenic-induced cancer has been widely studied, comparatively little attention has been paid to arsenic-induced vascular disease....
N-Isopropyl-3-methyl-2-nitrobenzamide (2009)
Yu Chen, Li-hua Guo, Wei Song, Jing Zhang, Dan-bi Tian
In the title compound, C11H14N2O3, the bond lengths and angles are within normal ranges. Weak intermolecular N—H...O interactions link the molecules into chains along the a axis. A...
3,3′-Dimethyl-1,1′-ethylenediimidazolium dibromide (2009)
Yu Chen, Wei Song, Juan Xu, Rui-bo Cui, Dan-bi Tian
The title compound, C10H16Br2N4, was synthesized by the reaction of 1-methylimidazole and 1,2-dibromoethane in toluene. The complete dication is generated by a crystallographic inversion centre...
1-Methyl-3-n-tetradecylimidazolium bromide monohydrate (2009)
Yu Chen, Wei Song, Juan Xu, Xiao-Rong Yang, Dan-Bi Tian
In the title ionic liquid salt hydrate, C18H35N2+·Br−·H2O, the side chain in the cation has an extended conformation. The crystal structure is stabilized primarily by O—H...Br...
Yu Chen, Andreas Eisele, Christian Federmann, Eva Hasler, Michael Jellinghaus, Silke Theison
We describe an architecture that allows to combine statistical machine translation (SMT) with rule-based machine translation (RBMT) in a multi-engine setup. We use a variant of standard SMT...
A distributed policy scheduling for wireless sensor networks (2008)
Abstract — We aim to save energy by scheduling periodic sensors ’ duty cycles. Different from existing works, we integrate two important tasks, collision avoidance and duty cycling, into one...
In this paper we present a rigorous treatment to structured overlay maintenance in decentralized peerto-peer (P2P) systems subject to various system and network failures. we present a precise...
Tag-based Multipath Geographic Routing (2008)
In this report, we study the tag-based multi-path routing in wireless networks. The main contribution of this work is the mapping from the tags to the paths. With the mapping, we are able to control...
Y. Chen, D. Xu, Yu Chen, Dong Xu
As we are moving into the post genome-sequencing era, various high-throughput experimental techniques have been developed to characterize biological systems at the genome scale. Discovering new...
BIOINFORMATICS ORIGINAL PAPER Structural bioinformatics (2008)
doi:10.1093/bioinformatics/btl351
The Dynamics of Public Opinion in Complex Networks (2008)
This paper studies the problem of public opinion formation and concentrates on the interplays among three factors: individual attributes, environmental influences and information flow. We present a...
Tian, Mei, Cui, Ya-Zhou, Song, Guan-Hua, Zong, Mei-Juan, Zhou, Xiao-Yan, Chen, Yu, ...
Abstract Background There is an urgent need to discover more sensitive and specific biomarkers to improve early diagnosis and screen high-risk patients for pancreatic ductal adenocarcinoma (PDAC)....
Wei Chen, Yu Chen, Jialin Zhang
In this paper, we apply the partition approach proposed in [6] to study weak failure detectors for set agreement problem for the shared-memory model. In a system with n + 1 processes, for any 2 ≤ k...
Xiangping Meng, Robert Babuška, Yu Chen, Lucian Busoniu, Xiangping Meng, Robert Babuška, ...
In this paper several multiagent reinforcement learning algorithms are investigated, compared and analyzed. An effective reinforcement learning algorithm based on non Markov environment is proposed....
Protection of Database Security via Collaborative Inference Detection 1 Abstract (2008)
Malicious users can exploit the correlation among data to infer sensitive information from a series of seemingly innocuous data accesses. Thus, we develop an inference violation detection system to...
Area Fill Generation With Inherent Data Volume Reduction \Lambda (2008)
Yu Chen, Andrew B. Kahng, Gabriel Robins Alex, Er Zelikovsky, Yuhong Zheng
Saccharomyces Cerevisiae, Trupti Joshi, Yu Chen, Jeffrey M. Becker, Nickolai Alexandrov, Dong Xu
Characterizing gene function is one of the major challenging tasks in the post-genomic era. To address this challenge, we have developed GeneFAS (Gene Function Annotation System), a new integrated...
A rotating black lens solution in five dimensions (2008)
It has recently been shown that a stationary, asymptotically flat vacuum black hole in five space-time dimensions with two commuting axial symmetries must have an event horizon with either a...
Surface modified silicon nanochannel for urea sensing (2008)
Chen, Yu, Wang, Xihua, Hong, Mi, Erramilli, Shyamsunder, Mohanty, Pritiraj
Silicon nanowires have been surface functionalized with the enzyme urease for biosensor applications to detect and quantify urea concentration. The device is nanofabricated from a silicon on...
Multiagent Reinforcement Learning Algorithm Research Based on Non Markov Environment (2008)
Xiangping Meng, Robert Babuška, Yu Chen, Lucian Busoniu
In this paper several multiagent reinforcement learning algorithms are investigated, compared and analyzed. An effective reinforcement learning algorithm based on non Markov environment is proposed....
1 Overview Research Statement (2008)
My research interests include theory of distributed computing, mobile computing and wireless networking. My research approaches encompass formal model, impossibility and upper/lower bound proofs,...
Constantino Tsallis (n, Alejandro Raúl Hernández, Akio Matsumoto, Akira Ishii, Hiroshi Sato, Hiroyuki Yoshida, ...
* N-220, N-232, N-332 are the names of rooms. * We are going to hold all sessions at SCIENCE HALL. (Please check with the Campus map of our university.) 23-Nov
Drug Exposure Side Effects from Mining Pregnancy Data (2008)
Yu Chen, Lars Henning, Pedersen Wesley, W. Chu, Jorn Olsen
This paper presents an interdisciplinary collaborative research project between the Epidemiology Department and the Computer Science Department for using data mining technique to analyze data from...
Collaborative change detection of DDoS attacks on community and (2008)
ABSTRACT ∗ A community network often operates within the same ISP (Internet Service Provider) domain or administered by a virtual organization spanning across multiple network domains with an...
Topology-transparent duty cycling for wireless sensor networks (2008)
Abstract — Our goal is to save energy in wireless sensor networks (WSNs) by periodic duty-cycling of sensor nodes. We schedule sensor nodes between active (transmit or receive) and sleep modes...
Product Line Process Simulator (2008)
Yu Chen, Gerald C. Gannod, James S. Collofello, Yu Chen, Gerald C. Gannod, James S. Collofello, ...
Organizations are moving towards the use of software product line approaches to build product families. Cases have shown that software product line approaches can reduce time-to-market, costs, and...
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating high-throughput data...
Abstract Evaluation of the New OASIS Format for Layout Fill Compression ∗ (2008)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky, Yuhong Zheng
SIS) has been recently proposed for replacing the GDSII format. A primary objective of the new OASIS format is to enhance the compressibility of layout data. We compare the data compression...
List of Supported Students and Staff (2008)
Betty Salzberg, Betty Salzberg, Xiaowei Sun, Yu Chen, Ph. D. Students
Project Award Information
Yu Chen, Member Ieee, Kai Hwang, Fellow Ieee, Wei-shinn Ku
Abstract — This paper presents a new distributed approach to detecting DDoS (distributed denial of services) flooding attacks at the traffic flow level. The new defense system is suitable for...
Towards High Level Attack Scenario Graph through Honeynet Data Correlation Analysis (2008)
Jianwei Zhuge, Xinhui Han, Yu Chen, Zhiyuan Ye, Wei Zou
Abstract—Honeynet Data Analysis has become a core requirement of honeynet technology. However, current honeynet data analysis mechanisms are still unable to provide security analysts enough...
A Middleware Based Mobile Scientific Computing (2008)
Xi Wang, Xu Liu, Xiaoge Wang, Yu Chen
Abstract. In this paper we present a scientific computing system named MobileLab which is designed for pervasive computing on the Internet. A middleware named TOM (stands for Tsinghua Operation...
Chaitanya Bandela, Ion I. Măndoiu, Yu Chen, Andrew B. Kahng, Alexander Zelikovsky
Abstract. Auctions and exchanges are one of the most important market mechanisms for price determination and allocation of goods. In this paper we consider the case when each buyer has a limited...
Component Similarity Based Methods for Automatic Analysis of Malicious Executables (2008)
Zhiyin Liang, Tao Wei, Yu Chen, Xinhui Han, Jianwei Zhuge
Abstract. In recent years with the popularity of source code sharing, the number of types of malware increases sharply; furthermore, malwares are also getting more and more sophisticated. These...
Yu Chen, Andrew B. Kahng, Gabriel Robins
Control of variability in the back end of the line, and hence in interconnect performance as well, has become extremely difcult with the introduction of new materials such as copper and low-k...
ABSTRACT Performance-Impact Limited Area Fill Synthesis ∗ (2008)
Yu Chen, Puneet Gupta, Andrew B. Kahng
Chemical-mechanical planarization (CMP) and other manufacturing steps in very deep-submicron VLSI have varying effects on device and interconnect features, depending on the local layout density. To...
New Monte-Carlo Algorithms for Layout Density Control (2008)
Yu Chen, Andrew B. Kahng, Gabriel Robins Y, Er Zelikovsky Z
Abstract | Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying e ects on device and interconnect features, depending on local characteristics of...
Control of variability in the back end of the line, and hence in interconnect performance as well, has become extremely difficult with the introduction of new materials such as copper and low-k...
Channel-Width Dependent Enhancement in Nanoscale Field Effect Transistor (2008)
Wang, Xihua, Chen, Yu, Hong, Mi K., Erramilli, Shyamsunder, Mohanty, Pritiraj
We report the observation of channel-width dependent enhancement in nanoscale field effect transistors containing lithographically-patterned silicon nanowires as the conduction channel. These devices...
Silicon-based nanochannel glucose sensor (2008)
Wang, Xihua, Chen, Yu, Gibney, Katherine A., Erramilli, Shyamsunder, Mohanty, Pritiraj
Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface...
Nanoscale field effect transistor for biomolecular signal amplification (2008)
Chen, Yu, Wang, Xihua, Hong, Mi K., Erramilli, Shyamsunder, Rosenberg, Carol, Mohanty, Pritiraj
We report amplification of biomolecular recognition signal in lithographically defined silicon nanochannel devices. The devices are configured as field effect transistors (FET) in the reversed...
Compact, time-harmonic, acoustic sources produce waves that decay too slowly to be square-integrable on a line away from the sources. We introduce an inner product, arising directly from Green’s...
Abstract Evaluation of the New OASIS Format for Layout Fill Compression ∗ (2008)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky, Yuhong Zheng
SIS) has been recently proposed for replacing the GDSII format. A primary objective of the new OASIS format is to enhance the compressibility of layout data. We compare the data compression...
Kai Hwang, Min Cai, Yu-kwong Kwok, Shanshan Song, Yu Chen, Ying Chen
security infrastructure for trusted internet
Control of variability in the back end of the line, and hence in interconnect performance as well, has become extremely difficult with the introduction of new materials such as copper and low-k...
Abstract Area Fill Generation With Inherent Data Volume Reduction (2008)
Yu Chen, Andrew B. Kahng, Gabriel Robins Alex, Er Zelikovsky, Yuhong Zheng
Control of variability and performance in the back end of the VLSI manufacturing line has become extremely difficult with the introduction of new materials such as copper and low-k dielectrics....
Leveraging Visio for Adoption-Centric Reverse Engineering Tools (2008)
Qin Zhu, Yu Chen, Piotr Kaminski, Anke Weber, Holger Kienle, Hausi A. Müller
There are many reasons why reverse engineering research tools often fail to be evaluated or adopted in industry. Their rough user interfaces and poor interoperability are just two frequently...
Yu Chen, Yunfei Liu, Hui-Min Tan
Superabsorbent polymer was prepared by graft polymerization of acrylic acid onto the chain of carboxymethyl cellulose. This superabsorbent polymer was further treated by the solvent precipitation...
Guangyu Cui, Yu Chen, De-Shuang Huang, Kyungsook Han
Biological processes are often performed by a group of proteins rather than by individual proteins, and proteins in a same biological group form a densely connected subgraph in a protein-protein...
Guangyu Cui, Yu Chen, De-Shuang Huang, Kyungsook Han
Biological processes are often performed by a group of proteins rather than by individual proteins, and proteins in a same biological group form a densely connected subgraph in a protein-protein...
Chen, Yu, Gammon, Marilie D., Teitelbaum, Susan L., Britton, Julie A., Terry, Mary Beth, Shantakumar, Sumitra, ...
The genes that are involved in estrogen biosynthesis, cellular binding and metabolism may contribute to breast cancer susceptibility. We examined the effect of the CYP17 promoter T → C polymorphism...
Cell-free selection of RNA-binding proteins using in vitro compartmentalization (2008)
Chen, Yu, Mandic, Jana, Varani, Gabriele
RNA-binding proteins (RBPs) perform many essential functions in the post-transcriptional control of gene expression. If we were able to engineer RBPs with new specificity, it would also become...
Assessment of skin dose for breast chest wall radiotherapy as a function of bolus material (2008)
Hsu, Shu-Hui, Roberson, Peter L, Chen, Yu, Marsh, Robin B, Pierce, Lori J, Moran, Jean M
"Skin dose assessment for chest wall radiotherapy is important to ensure sufficient dose to the surface target volume without excessive skin reaction. This study quantified changes to the surface...
Chen, Mao, Sandow, Shaun L, Doceul, Virginie, Chen, Yu, Harper, Heather, Hamilton, Bruce, ...
Abstract Background HERG potassium channel blockade is the major cause for drug-induced long QT syndrome, which sometimes cause cardiac disrhythmias and sudden death. There is a strong interest in...
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Abstract--- To improve manufacturability and performance predictability, we seek to make a layout uniform with respect to prescribed density criteria, by inserting "fill "...
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Abstract--- To improve manufacturability and performance predictability, we seek to make a layout uniform with respect to prescribed density criteria, by inserting "fill "...
Monte-Carlo Algorithms for Layout Density Control (2007)
Yu Chen Andrew, Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on local characteristics of the...
Abstract Area Fill Generation With Inherent Data Volume Reduction (2007)
Yu Chen, Andrew B. Kahng, Gabriel Robins Alex, Er Zelikovsky, Yuhong Zheng
Control of variability and performance in the back end of the VLSI manufacturing line has become extremely difficult with the introduction of new materials such as copper and low-k dielectrics....
1 Area Fill Synthesis for Uniform Layout Density (2007)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
Abstract--- Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on local characteristics...
Closing the Smoothness and Uniformity Gap in Area Fill Synthesis (2007)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Control of variability in the back end of the line, and hence in interconnect performance as well, has become extremely difficult with the introduction of new materials such as copper and low-k...
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Chemical-mechanical planarization (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on the local layout density. To...
IDNS: A SIMPLE APPROACH TO INTERNET HOST PORTABILITY (2007)
Abstract: Current mobile networking applications can be classified into two categories--- mobility and portability. Mobility means the capability of transacting continuous network traffic and...
Dynamic Home Agent Reassignment in Mobile IP (2007)
Abstract- Under conventional Mobile IP, all traffic to a MN is tunneled to the current Foreign Agent (FA) from the remote HA, which can result in poor efficiency. Dynamic Home Agent (HA) reassignment...
Telelearning Applications Examining Committee: (2007)
ii Telelearning is a collection of strategies and techniques for instruction at a distance. With the relatively recent success of the Internet and its almost universal accessibility, the web has...
IDNS: A SIMPLE APPROACH TO INTERNET HOST PORTABILITY (2007)
Abstract: Current mobile networking applications can be classified into two categories--- mobility and portability. Mobility means the capability of transacting continuous network traffic and...
A Representation of Acoustic Waves (2007)
In Unbounded Domains, Bradley K. Alpert, Yu Chen
this paper an inner product and use it to construct an orthogonal basis for all outgoing waves from D. In other words, we will present a method to eciently sample the outgoing wave functions on the...
[Software]: Miscellaneous General Terms (2007)
Helen J. Wang, John Platt, Yu Chen, Ruyun Zhang, Yi-min Wang
Technical support contributes 17 % of the total cost of ownership of today’s desktop PCs [3]. An important element of technical support is troubleshooting misconfigured applications....
Efficacy of different protein descriptors in predicting protein functional families (2007)
Ong, Serene AK, Lin, Hong, Chen, Yu, Li, Ze, Cao, Zhiwei
Abstract Background Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a need to...
Adams, L. L. A., Lang, B. W., Chen, Yu, Goldman, A. M.
Lead clusters deposited on Si(111) substrates have been studied at low temperatures using scanning tunneling microscopy and spectroscopy. The current-voltage characteristics exhibit current peaks...
Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons (2007)
Zelda H. Cheung, Wing Hong Chin, Yu Chen, Yu Pong Ng, Nancy Y. Ip
Neurotrophins are key regulators of neuronal survival and differentiation during development. Activation of their cognate receptors, Trk receptors, a family of receptor tyrosine kinases (RTKs), is...
Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons (2007)
Cheung, Zelda H., Chin, Wing Hong, Chen, Yu, Ng, Yu Pong, Ip, Nancy Y.
Neurotrophins are key regulators of neuronal survival and differentiation during development. Activation of their cognate receptors, Trk receptors, a family of receptor tyrosine kinases (RTKs), is...
Yu Chen, Mohammad Enamul Hakim, Faruque Parvez, Tariqul Islam, Atiar M. Rahman, Habibul Ahsan
Epidemiological studies have linked high levels (>200 μg/L) of chronic exposure to arsenic in drinking-water with elevated risks of several vascular diseases. In this pilot study, the association...
Fu, Wing Yu, Chen, Yu, Sahin, Mustafa, Zhao, Xioaosu, Shi, Lei, Bikoff, Jay B., ...
The development of dendritic spines is thought to be crucial for synaptic plasticity. Dendritic spines are retracted upon EphA4 activation, but the mechanisms that control this process are not well...
We consider sensor networks for monitoring tasks, where data of each stimulus is required to be collected by at least one of potentially multiple, mobile nodes, called sinks. We propose a...
We consider sensor networks for monitoring tasks, where data of each stimulus is required to be collected by at least one of potentially multiple, mobile nodes, called sinks. We propose a...
Regulation of EphA4-dependent signaling at synapses (2007)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2007
Regulation of EphA4-dependent signaling at synapses / (2007)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2007.
Cited2 is required for normal hematopoiesis in the murine fetal liver. (2007)
Chen, Yu, Haviernik, Peter, Bunting, Kevin D., Yang, Yu-Chung
Cited2 (cAMP-responsive elementbinding protein [CBP]/p300-interacting transactivators with glutamic acid [E] and aspartic acid [D]-rich tail 2) is a newly identified transcriptional modulator....
Cited2, a coactivator of HNF4alpha, is essential for liver development. (2007)
Qu, Xiaoling, Lam, Eric, Doughman, Yong-Qiu, Chen, Yu, Chou, Yu-Ting, Lam, Minh, ...
The transcriptional modulator Cited2 is induced by various biological stimuli including hypoxia, cytokines, growth factors, lipopolysaccharide (LPS) and flow shear. In this study, we report that...
PET reconstruction using generalized natural pixels and a Monte Carlo generated system matrix (2007)
YU CHEN, Vandenberghe, Stefaan, Staelens, Steven, Verhaeghe, Jeroen, GLICK, S.J.
Partition approach to failure detectors for k-set agreement (2007)
Wei Chen, Jialin Zhang, Yu Chen, Xuezheng Liu
In k-set agreement problem, every process proposes a value and eventually at most k different values can be decided. When k> 1, different subset of processes may decide on different values, and...
CELCT GROUP Technologies (2007)
Yu Chen, Andreas Eisele, Christian Federmann, Jellinghaus Silke Theison, Ist Deliverable D, Silke Theison, ...
Project funded by the European Community under the Sixth Framework Programme for Research and Technological Development. Project ref no. IST-034291
Failure detectors and extended Paxos for k-set agreement (2007)
Wei Chen, Jialin Zhang, Yu Chen, Xuezheng Liu
Failure detector class Ωk has been defined in [17] as an extension to failure detector Ω, and an algorithm has been given in [15] to solve k-set agreement using Ωk in asynchronous...
Weakening failure detectors for k-set agreement via the partition approach (2007)
Wei Chen, Jialin Zhang, Yu Chen, Xuezheng Liu
Abstract. In this paper, we propose the partition approach and define several new classes of partitioned failure detectors weaker than existing failure detectors for the k-set agreement problem in...
Decentralized, connectivity-preserving, and cost-effective structured overlay maintenance (2007)
Abstract. In this paper we present a rigorous treatment to structured overlay maintenance in decentralized peer-to-peer (P2P) systems subject to various system and network failures. We present a...
Chen, Yu, Factor-Litvak, Pam, Howe, Geoffrey R., Graziano, Joseph H., Brandt-Rauf, Paul, Parvez, Faruque, ...
The authors performed a cross-sectional analysis to evaluate the association between arsenic exposure from drinking water and blood pressure using baseline data of 10,910 participants in the Health...
Fold Recognition via a Tree (2006)
Recently, we developed a pairwise structural alignment algorithm using realistic structural and environmental information (SAUCE). In this paper, we at first present an automatic fold hierarchical...
Dominant regions in noncrystallographic hyperplane arrangements (2006)
For a crystallographic root system, dominant regions in the Catalan hyperplane arrangement are in bijection with antichains in a partial order on the positive roots. For a noncrystallographic root...
Eel population and solution model (2006)
Chen, Liangming, Chen, Xinyu, Chen, Yu, Fang, Ping, Huang, Yuyu, Li, Haiyan, ...
Almost two decades before, eel population had not waved quite hugely, but in this twenty years, it is changed. Eel population decreases very obviously on account of five main reasons—pollution,...
Duplicate Address Detection in Wireless Ad Hoc Networks Using Wireless Nature (2006)
We consider duplicate address detection in wireless ad hoc networks under the assumption that addresses are unique in two hops neighborhood. Our approaches are based on the concepts of physical...
Duplicate Address Detection in Wireless Ad Hoc Networks Using Wireless Nature (2006)
We consider duplicate address detection in wireless ad hoc networks under the assumption that addresses are unique in two hops neighborhood. Our approaches are based on the concepts of physical...
Thesis (Ph. D.)--University of Washington, 2006.
A process-centric framework for software product line evolution management / (2006)
Thesis (Ph. D.)--Arizona State University, 2006.
Database Security Protection via Inference Detection (2006)
Abstract. Access control mechanisms are commonly used to provide control over who may access sensitive information. However, malicious users can exploit the correlation among the data and infer...
Objectives: Heat shock and elevated expression of heat shock proteins suppress activation of the pro-inflammatory transcription factor NF-B. We hypothesized that knocking down the expression of heat...
An iterative refinement algorithm for consistency based multiple structural alignment methods (2006)
Motivation: Multiple STructural Alignment (MSTA) provides valuable information for solving problems such as fold recognition. The consistency-based approach tries to find conflict-free subsets of...
CHEN, Yu, ZHANG, XuDong, WANG, DeSheng
A novel error detection method based on coded block pattern (CBP) information verification is proposed for error concealment of inter-coded video frames transmitted in wireless channel. This method...
CHEN, Yu, ZHANG, XuDong, WANG, DeSheng
Based on the observation that foveation analysis can be used to find most critical content in terms of human visual perception in video and image, one effective error resilience method is proposed...
Ahsan, Habibul, Chen, Yu, Parvez, Faruque, Zablotska, Lydia, Argos, Maria, Hussain, Iftikhar, ...
Millions of persons around the world are exposed to low doses of arsenic through drinking water. However, estimates of health effects associated with low-dose arsenic exposure have been extrapolated...
Dietary factors, arsenic exposure, and risk of high blood pressure in Bangladesh (2005)
The objectives of this dissertation are to: (1)Â assess the validity of a food frequency questionnaire (FFQ) designed for the Health Effects of Arsenic Longitudinal Study (HEALS); (2)Â examine...
Thesis (M.S.)--Kansas State University, 2005.
Once ever : a narrative short [electronic resource] / (2005)
This thesis book describes the development and production of Once Ever, a short narrative film. The writing, pre-production, shooting, and editing of the film is reviewed. Script drafts and a final...
BitVault: a Highly Reliable Distributed Data Retention Platform (2005)
Zheng Zhang, Qiao Lian, Shiding Lin, Wei Chen, Yu Chen, Chao Jin
This paper summarizes our experience designing and implementing BitVault: a content-addressable retention platform for large volumes of reference data � seldomchanging information that needs to be...
Yu-kwong Kwok, Rohit Tripathi, Yu Chen, Kai Hwang
High availability in network services is crucial for effective largescale distributed computing. While distributed denial-of-service (DDoS) attacks through massive packet flooding have baffled...
MAFIC: Adaptive Packet Dropping for Cutting Malicious Flows to Push Back DDoS Attacks (2005)
Yu Chen, Yu-kwong Kwok, Kai Hwang
In this paper, we propose a new approach called MAFIC (MAlicious Flow Identification and Cutoff) to support adaptive packet dropping to fend off DDoS attacks. MAFIC works by judiciously issuing...
Kai Hwang, Yu-kwong Kwok, Shanshan Song, Min Cai, Yu Chen, Ying Chen, ...
The USC GridSec project develops distributed security infrastructure and self-defense capabilities to secure wide-area networked resource sites participating in a Grid application. We report new...
Min Cai, Kai Hwang, Yu-kwong Kwok, Shanshan Song, Yu Chen
Abstract: Internet catastrophes could be caused by large-scale worm outbreaks that lead to DDoS flooding attacks. Internet worms can be exploited to damage infected hosts and launch flooding attacks...
MAFIC: Adaptive Packet Dropping for Cutting Malicious Flows to Pushback DDoS (2005)
Yu Chen, Yu-kwong Kwok, Kai Hwang
Abstract — In this paper, we propose a new approach
Yu Chen, Kai Hwang, Yu-kwong Kwok
Abstract: The shrew or pulsing DDoS (Distributed Denial-of-Service) attacks, also known as RoQ (Reduction of Quality) attacks, are stealthy, periodic, and low-rate in volume. The shrew attacks could...
Compressible area fill synthesis (2005)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky, Yuhong Zheng
Abstract—Control of variability and performance in the back end of the VLSI manufacturing line has become extremely difficult with the introduction of new materials such as copper and low-k...
Filtering Shrew DDoS Attacks Using A New Frequency-Domain Approach (2005)
Yu Chen, Yu-kwong Kwok, Kai Hwang
known as Reduction of Quality (RoQ) attacks, could be even more detrimental than the more widely known flooding DDoS assaults. The reason is that such shrew attacks damage the victim servers for a...
Kai Hwang, Yu-kwong Kwok, Shanshan Song, Min Cai, Yu Chen, Ying Chen, ...
Abstract: The USC GridSec project develops distributed security infrastructure and self-defense capabilities to secure wide-area networked resource sites participating in a Grid application. We...
Compressible area fill synthesis (2005)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky, Yuhong Zheng
Control of variability and performance in the back end of the VLSI manufacturing line has become extremely difficult with the introduction of new materials such as copper and low-k dielectrics. To...
DESIGN AND ANALYSIS OF DISTRlBUTED PRIMITIVES FOR MOBILE AD HOC Approved by: NETWORKS (2005)
This dissertation focuses on the design and analysis of distributed primitives for mobile ad hoc networks, in which mobile hosts are free to move arbitrarily. Arbitrary mobility adds unpredictability...
Microsoft Research,Asia Adapting Web Pages for Small-Screen Devices (2005)
Most of the Web pages in existence today were designed for desktop PCs,which makes viewing them on mobile Web browsers extremely difficult.The authors developed new page-adaptation technique analyzes...
Dissertation (Ph.D.)--University of Michigan.
Dietary factors, arsenic exposure, and risk of high blood pressure in Bangladesh (2005)
Department: Epidemiology.
Shan, Xiaohui, Liu, Zhenlan, Dong, Zhenying, Wang, Yongming, Chen, Yu, Lin, Xiuyun, ...
Hybridization between different species plays an important role in plant genome evolution, as well as is a widely used approach for crop improvement. McClintock has predicted that plant wide...
Motivation: Protein dispensability is fundamental to the understanding of gene function and evolution. Recent advances in generating high-throughput data such as genomic sequence data,...
Shan, Xiaohui, Liu, Zhenlan, Dong, Zhenying, Wang, Yongming, Chen, Yu, Lin, Xiuyun, ...
Hybridization between different species plays an important role in plant genome evolution, as well as is a widely used approach for crop improvement. McClintock has predicted that plant wide...
Zhang, Jinfeng, Chen, Yu, Chen, Rong, Liang, Jie
In simple models side chains are often represented implicitly (e.g., by spin-states) or simplified as one atom. We study side chain effects using square lattice and tetrahedral lattice models, with...
P2P Resource Pool and Its Application to Optimize WideArea Application Level Multicasting (2004)
Zheng Zhang, Yu Chen, Shi-ding Lin, Bo-ying Lu, Shu-ming Shi, Xing Xie, ...
The concept of resource pool has a very long history. Propelled by the need to share CPU cycles of supercomputers for highthroughput computing jobs from the scientific community, the vision is most...
Navneet Malpani, Yu Chen, Nitin H. Vaidya, Jennifer L. Welch
This paper presents several distributed algorithms that cause a token to continually circulate through all the nodes of a mobile ad hoc network. An important application of such algorithms is to...
Automatic Misconfiguration Troubleshooting with PeerPressure (2004)
Helen J. Wang, John C. Platt, Yu Chen, Ruyun Zhang, Yi-min Wang
Technical support contributes 17 % of the total cost of ownership of today’s desktop PCs [25]. An important element of technical support is troubleshooting misconfigured applications....
Automatic Misconfiguration Troubleshooting with PeerPressure (2004)
Helen J. Wang, John C. Platt, Yu Chen, Ruyun Zhang, Yi-min Wang
Abstract — Technical support contributes 17 % of the total cost of ownership of today’s desktop PCs [25]. An important element of technical support is troubleshooting misconfigured applications....
Automatic Misconfiguration Troubleshooting with PeerPressure (2004)
Helen J. Wang, John C. Platt, Yu Chen, Ruyun Zhang, Yi-min Wang
Technical support contributes 17 % of the total cost of ownership of today’s desktop PCs [25]. An important element of technical support is troubleshooting misconfigured applications....
An error concealment algorithm for entire frame loss in video transmission (2004)
Yu Chen, Keman Yu, Jiang Li, Shipeng Li
In video transmission over the Internet, the quality of service is usually not guaranteed. The loss of a packet may result in the loss of a whole video frame. While most of the current error...
Motivation: Protein dispensability is fundamental to understanding of gene function and evolution. Recent advances in generating high-throughput data such as genomic sequence data, protein-protein...
As we are moving into the post genome-sequencing era, various high-throughput experimental techniques have been developed to characterize biological systems on the genomic scale. Discovering new...
Chen, Yu, Kortemme, Tanja, Robertson, Tim, Baker, David, Varani, Gabriele
RNA-binding proteins play many essential roles in the regulation of gene expression in the cell. Despite the significant increase in the number of structures for RNA–protein complexes in the last...
Motivation: Protein dispensability is fundamental to understanding of gene function and evolution. Recent advances in generating high-throughput data such as genomic sequence data, protein-protein...
F-actin and myosin II binding domains in supervillin (2003)
Chen, Yu, Takizawa, Norio, Crowley, Jessica Lynn, Oh, Sang W., Gatto, Cheryl Lynn, Kambara, Taketoshi, ...
Detergent-resistant membranes contain signaling and integral membrane proteins that organize cholesterol-rich domains called lipid rafts. A subset of these detergent-resistant membranes (DRM-H)...
Diffuse optical spectroscopy (DOS) and tomography (DOT) using Near-Infrared (NIR) light provide promising tools for non-invasive imaging and clinical diagnosis of deep tissue. These techniques are...
We address the worst-case adaptive controller design for single-input linear systems with repeated noisy measurements of a particular linear combination of the state variables to achieve asymptotic...
Lin, Juan, Chen, Yu, Xu, Ying, Yan, Fang, Tang, Lin, Chen, Fang
Curcin, a ribosome-inactivating protein with a molecular weight of about 28.2 kD, which stronglyinhibits the protein synthesisin rabbit reticulocytelysate system with an IC50 value of about (0.19 ±...
Thesis (M.S.)--University of Cincinnati, 2003.
Computational analyses of high-throughput protein–protein interaction data (2003)
Abstract: Protein-protein interactions play important roles in nearly all events that take place in a cell. High-throughput experimental techniques enable the study of protein-protein interactions at...
Enabling Multimedia Adaptation Services in Content Delivery Networks. IMMCN’03 (2003)
Wei-ying Ma, Xing Xie, Chun Yuan, Yu Chen, Zheng Zhang, Hong-jiang Zhang
Content delivery networks (CDNs) provide a large number of caches and storage devices at the edge of network to push content closer to the user. To cope with the growing diversity and heterogeneity...
STRIDER: A Black-box, State-based Approach to Change and Configuration Management and Support (2003)
Yi-min Wang, Chad Verbowski, John Dunagan, Yu Chen, Helen J. Wang, Chun Yuan
Permission is granted for noncommercial reproduction of the work for educational or research purposes.
PeerPressure: A Statistical Method for Automatic Misconfiguration Troubleshooting (2003)
Helen J. Wang, Helen J. Wang, John Platt, John Platt, Yu Chen, Yu Chen, ...
Technical support contributes 17% of the total cost of ownership of today's desktop PCs [20]. An important element of technical support is troubleshooting misconfigured applications....
Evaluation of edge caching/offloading for dynamic content delivery (2003)
Chun Yuan, Yu Chen, Zheng Zhang
Abstract—As dynamic content becomes increasingly dominant, it becomes an important research topic as how the edge resources such as client-side proxies, which are otherwise underutilized for such...
Performance-impact limited area fill synthesis (2003)
Yu Chen, Puneet Gupta, Andrew B. Kahng
Chemical-mechanical planarization (CMP) and other manufacturing steps in very deep-submicron VLSI have varying effects on device and interconnect features, depending on the local layout density. To...
STRIDER: A Black-box, State-based Approach to Change and Configuration Management and Support (2003)
Yi-min Wang, Chad Verbowski, John Dunagan, Yu Chen, Helen J. Wang, Chun Yuan
We describe a new approach, called Strider, to Change and Configuration Management and Support (CCMS). Strider is a black-box approach: without relying on specifications, it uses state differencing...
Detecting Web Page Structure for Adaptive Viewing on Small Form Factor Devices (2003)
Mobile devices have already been widely used to access the Web. However, because most available web pages are designed for desktop PC in mind, it is inconvenient to browse these large web pages on a...
Layout density control for improved VLSI manufacturability / (2003)
Thesis (Ph. D.)--University of California, Los Angeles, 2003.
On the combinatorics of $B \times B$-orbits on group compactifications (2002)
It is shown that there is an order isomorphism $\phi'$ from the poset $V$ of $B\times B$-orbits on the wonderful compactification of a semi-simple adjoint group $G$ with Weyl group $W$ to an interval...
This thesis presents exploratory work on the jet-cooled molecular clusters of coumarins and aminophthalimides, especially in the electronically excited state, using mainly the IR-UV double-resonance...
Flp recombinase : structural and functional studies / (2002)
Thesis (Ph. D.)--University of Chicago, Dept. of Biochemistry and Molecular Biology, December 2002.
Flp recombinase : structural and functional studies / (2002)
Thesis (Ph. D.)--University of Chicago, Dept. of Biochemistry and Molecular Biology, December 2002.
Area fill synthesis for uniform layout density (2002)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
Abstract — Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on local characteristics...
Self-stabilizing mutual exclusion using tokens in mobile ad hoc networks (2002)
In this paper, we propose a self-stabilizing mutual exclusion algorithm using tokens for mobile ad hoc networks. Our algorithm is based on dynamic virtual rings formed by circulating tokens. We...
Area fill synthesis for uniform layout density (2002)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
Abstract — Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on local characteristics...
Vibration characteristics and integral passive damping of composite isogrid structures (2001)
Composite isogrid structures are currently used in aerospace applications and have great potential in engineering applications such as those in the automotive industry. However, a literature review...
S-Nets : smart sensor networks / (2001)
Thesis (M.S.)--Dept. of Bioengineering, University of Utah, 2001.
A distributed component integration tool / (2001)
Thesis (M.S.)--Arizona State University, 2001.
Vibration characteristics and integral passive damping of composite isogrid structures / (2001)
Typescript.
Distributed Token Circulation in Mobile Ad Hoc Networks (2001)
Navneet Malpani, Yu Chen, Nitin H. Vaidya, Senior Member, Jennifer L. Welch
Abstract—This paper presents several distributed algorithms that cause a token to continually circulate through all the nodes of a mobile ad hoc network. An important application of such algorithms...
Hierarchical Dummy Fill for Process Uniformity (2001)
Yu Chen, Gabriel Robins Z, Er Zelikovsky
Abstract | To improve manufacturability and performance predictability, we seek to make alayout uniform with respect to prescribed density criteria, by inserting \ ll " geometries into the...
Mathematical modeling of scroll compressors (2000)
This thesis presents the development of a comprehensive R-410A scroll compressor model. The model is based on a previously existing R-22 scroll compressor model. This comprehensive compressor model...
Berners-Price, Sue, Parkinson, John A., Chen, Yu., Murdoch, Piedad. Del Socorro, Guo, Zijian., Brown, Tom., ...
Yes
Marburg, University, Diss., 2000.
Berners-Price, Sue, Parkinson, John A., Chen, Yu., Murdoch, Piedad. Del Socorro, Guo, Zijian., Brown, Tom., ...
Towards anisotropy in ordered conducting polymers. (2000)
Thesis (Ph. D.)--University of Aberdeen, May 2000.
Practical Iterated Fill Synthesis for CMP Uniformity (2000)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
We propose practical iterated methods for layout density control for CMP uniformity, based on linear programming, Monte-Carlo and greedy algorithms. We experimentally study the tradeoffs between two...
Practical Iterated Fill Synthesis for CMP Uniformity (2000)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
We propose practical iterated methods for layout density control for CMP uniformity, based on linear programming, Monte-Carlo and greedy algorithms. We experimentally study the tradeoffs between two...
Monte-Carlo Algorithms for Layout Density Control (2000)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
Chemical-mechanical polishing (CMP) and other manufacturing steps in very deep submicron VLSI have varying effects on device and interconnect features, depending on local characteristics of the...
Practical Iterated Fill Synthesis for CMP Uniformity (2000)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Alexander Zelikovsky
We propose practical iterated methods for layout density control for CMP uniformity, based on linear programming, Monte-Carlo and greedy algorithms. We experimentally study the tradeoffs between two...
Practical Iterated Fill Synthesis for CMP Uniformity (2000)
Yu Chen, Andrew B. Kahng, Gabriel Robins, Er Zelikovsky
We propose practical iterated methods for layout density control for CMP uniformity, based on linear programming, Monte-Carlo and greedy algorithms. We experimentally study the tradeoffs between two...
Marburg, University, Diss., 2000.
Berners-Price, Sue, Parkinson, John A., Chen, Yu., Murdoch, Piedad. Del Socorro, Guo, Zijian., Brown, Tom., ...
COUMARIN DYES AND WATER: HYDROGEN-BONDING INTERACTIONS STUDIED IN A SUPERSONIC JET (1999)
Palmer, Phillip M., Chen, Yu, Topp, Michael R.
Author Institution: Department of Chemistry, University of Pennsylvania
Development of a content-based indexing and retrieval system for MPEG video sequences / (1999)
Thesis (M.Eng.)--Nanyang Technological University, School of Electrical and Electronic Engineering, 1999.
On the associative-skew clock routing problem (1999)
Yu Chen, Andrew B. Kahng, Gang Qu, Er Zelikovsky
We introduce the associative skew clock routing problem, which seeks a clock routing tree such that zero skew is preserved only within identified groups of sinks. The associative skew problem is...
The Associative-Skew Clock Routing Problem (1999)
Yu Chen Andrew, Yu Chen, Andrew B. Kahng, Gang Qu, Er Zelikovsky
We introduce the associative skew clock routing problem, which seeks a clock routing tree such that zero skew is preserved only within identified groups of sinks. The associative skew problem is...
The Associative-Skew Clock Routing Problem (1999)
Yu Chen, Andrew B. Kahng, Gang Qu, Alexander Zelikovsky, Er Zelikovsky
We introduce the associative skew clock routing problem, which seeks a clock routing tree such that zero skew is preserved only within identified groups of sinks. The associative skew problem is...
On the associative-skew clock routing problem (1999)
Yu Chen, Andrew B. Kahng, Gang Qu, Er Zelikovsky
We introduce the associative skew clock routing problem, which seeks a clock routing tree such that zero skew is preserved only within identified groups of sinks. The associative skew problem is...
Functions of Patched and Smoothened in transducing Hedgehog signal (1998)
During Drosophila wing development, the secreted protein Hedgehog (Hh) functions as a short range signal from the posterior (P) compartment to the anterior (A) compartment. The multi-pass...
Functions of patched and smoothened in transducing hedgehog signal (1998)
Department: Genetics and Development.
Rejuvenation of Sequoia sempervirens in Vitro: Changes in Isoesterases and Isoperoxidases (1996)
Huang, Hao-jen, Chen, Yu, Kuo, Jung-Lien, Kuo, Tsong-teh, Tzeng, Chai-chong, Huang, Bau-lian, ...
Rejuvenation, as evidenced by restored rooting competence, of Sequoia sempervirens by a series of repeated grafting of adult shoot tips onto juvenile rootstocks in vitro was confirmed. Complete...
Heidelberg, Univ., Diss., 1995.
A study of an electrochemical alcohol sensor / (1992)
Thesis (M. Phil.)--University of Essex, 1992.
On the inverse scattering problem for the Helmholtz equation in one dimension / (1992)
Abstract: "Interest in the numerical solution of acoustic inverse scattering problems arises in a number of areas. Examples include medical diagnostics, non-destructive industrial testing,...
Spherical wave reflection and transmission. (1992)
Thesis (Ph. D.)--Open University, 1992.
Thesis (Ph. D.)--University of South Florida, 1991.
Enterprise Niche and E-Business Strategy (1970)
This paper uses the principles of business ecology to analyze the problems in Chinas e-business construction and probe in the ways for enterprises in different niches to carry out e-business...
Network Externality Products C &Competition Strategy: An Experimental Economics Approach (1970)
Geng Zhou, Jiaofei Zhong, Han Zhou, Yu Chen
Based on the theory of Complexity Adaptive System (CAS) and methods of experimental economics, using Multi-Agent-Based Simulation, we build a model of the network externality product market with the...
IOS Enabled Business Process Transformation: A Case Study in China (1970)
Luchuan Liu, Wanjin Hu, Yu Chen
Taking Chinas two successful IOSs as study subject, this paper investigated inter-firm business process transformation enabled by IOS from four aspects, namely, integration, transfer, elimination and...
A Model of Collaborative Knowledge-Building Based on Web2.0 (1970)
Rong Wang, Meiqi Fang, Yu Chen
The ubiquitous linking of computers in local and global networks makes possible the sharing of thoughts by people who are separated spatially or temporally. Many efforts are made to increase...
We address the worst-case adaptive controller design for single-input linear systems with repeated noisy measurements of a particular linear combination of the state variables to achieve asymptotic...
Tamoxifen inhibits acidification in cells independent of the estrogen receptor
Altan, Nihal, Chen, Yu, Schindler, Melvin, Simon, Sanford M.
Tamoxifen has been reported to have numerous physiological effects that are independent of the estrogen receptor, including sensitization of resistant tumor cells to many chemotherapeutic agents....
Impaired JAK-STAT signal transduction contributes to growth hormone resistance in chronic uremia
Schaefer, Franz, Chen, Yu, Tsao, Tanny, Nouri, Pouneh, Rabkin, Ralph
Chronic renal failure (CRF) is associated with resistance to the growth-promoting and anabolic actions of growth hormone (GH). In rats with CRF induced by partial renal ablation, 7 days of GH...
Shen, Zhi-Xiang, Shi, Zhan-Zhong, Fang, Jing, Gu, Bai-Wei, Li, Jun-Min, Zhu, Yong-Mei, ...
Both all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) have proven to be very effective in obtaining high clinical complete remission (CR) rates in acute promyelocytic leukemia (APL), but...
Chen, Yu, Kortemme, Tanja, Robertson, Tim, Baker, David, Varani, Gabriele
RNA-binding proteins play many essential roles in the regulation of gene expression in the cell. Despite the significant increase in the number of structures for RNA–protein complexes in the last...
No major association between TGFBR1*6A and prostate cancer
Kaklamani, Virginia, Baddi, Lisa, Rosman, Diana, Liu, Junjian, Ellis, Nathan, Oddoux, Carole, ...
Prostate cancer is the most commonly diagnosed cancer in men and one of the leading causes of cancer deaths. There is strong genetic evidence indicating that a large proportion of prostate cancers...
As we are moving into the post genome-sequencing era, various high-throughput experimental techniques have been developed to characterize biological systems on the genomic scale. Discovering new...
Heat shock treatment protects against angiotensin II–induced hypertension and inflammation in aorta
Chen, Yu, Ross, Brenda M., Currie, R. William
Angiotensin II (Ang II) is a potent vasoconstrictor and induces inflammation and end-organ injury through its activation of the proinflammatory transcription factor, nuclear factor–κB (NF-κB)....
Hussain, Snawar, Pan, Ji'an, Chen, Yu, Yang, Yalin, Xu, Jing, Peng, Yu, ...
The expression of the genomic information of severe acute respiratory syndrome coronavirus (SARS CoV) involves synthesis of a nested set of subgenomic RNAs (sgRNAs) by discontinuous transcription. In...
Flow through a Collapsible Tube: Experimental Analysis and Mathematical Model
Katz, Adolph I., Chen, Yu, Moreno, Augusto H.
Flow through thin-wall axisymmetric tubes has long been of interest to physiologists. Analysis is complicated by the fact that such tubes will collapse when the transmural pressure (internal minus...
Parvez, Faruque, Chen, Yu, Argos, Maria, Momotaj, Hassina, Dhar, Ratan, ...
We conducted a population-based prevalence survey in Araihazar, Bangladesh, to describe the distribution of arsenic exposure in a rural Bangladeshi population and to assess the population’s...
Cancer Burden From Arsenic in Drinking Water in Bangladesh
We assessed the potential burden of internal cancers due to arsenic exposure in Bangladesh. We estimated excess lifetime risks of death from liver, bladder, and lung cancers using an exposure...
Hou, Wan-ru, Chen, Yu, Wu, Xia, Hu, Jin-chu, Peng, Zheng-song, Yang, Jung, ...
We obtained the complete mitochondrial genome of U.thibetanus mupinensis by DNA sequencing based on the PCR fragments of 18 primers we designed. The results indicate that the mtDNA is 16 868 bp in...
Background: The nutritional determinants of hypertension in Bangladesh and other low-income countries are largely unknown. Objective: We assessed the associations of general hypertension with...
Chen, Yu, Van Geen, Alexander, Graziano, Joseph H., Pfaff, Alexander, Madajewicz, Malgosia, Parvez, Faruque, ...
p75 Neurotrophin Receptor Suppresses the Proliferation of Human Gastric Cancer Cells
Jin, Haifeng, Pan, Yanglin, Zhao, Lina, Zhai, Huihong, Li, Xiaohua, Sun, Li, ...
Identifying an effective therapeutic target is pivotal in the treatment of gastric cancer. In this study, we investigated the expression of p75 neurotrophin receptor (p75NTR) in gastric cancer and...
Structure of stem-loop IV of Tetrahymena telomerase RNA
Chen, Yu, Fender, Jessica, Legassie, Jason D, Jarstfer, Michael B, Bryan, Tracy M, Varani, Gabriele
Conserved domains within the RNA component of telomerase provide the template for reverse transcription, recruit protein components to the holoenzyme and are required for enzymatic activity. Among...
Chen, Yu, Santella, Regina M., Kibriya, Muhammad G., Wang, Qiao, Kappil, Maya, Verret, Wendy J., ...
Stehman, Stephanie A., Chen, Yu, McKenney, Richard J., Vallee, Richard B.
NudE and NudEL are related proteins that interact with cytoplasmic dynein and LIS1. Their functional relationship and involvement in LIS1 and dynein regulation are not completely understood. We find...
Parvez, Faruque, Chen, Yu, Brandt-Rauf, Paul W., Bernard, Alfred, Dumont, Xavier, Slavkovich, Vesna, ...
Tsai, Jin-Wu, Chen, Yu, Kriegstein, Arnold R., Vallee, Richard B.
Mutations in the human LIS1 gene cause the smooth brain disease classical lissencephaly. To understand the underlying mechanisms, we conducted in situ live cell imaging analysis of LIS1 function...
Luo, Shuo, Chen, Yu, Lai, Kwok-On, Arévalo, Juan Carlos, Froehner, Stanley C., Adams, Marvin E., ...
EphA4 signaling has recently been implicated in the regulation of synapse formation and plasticity. In this study, we show that ankyrin repeat-rich membrane spanning (ARMS; also known as a kinase...
A novel approach to structural alignment using realistic structural and environmental information
In the era of structural genomics, it is necessary to generate accurate structural alignments in order to build good templates for homology modeling. Although a great number of structural alignment...
Cui, Guangyu, Chen, Yu, Huang, De-Shuang, Han, Kyungsook
Biological processes are often performed by a group of proteins rather than by individual proteins, and proteins in a same biological group form a densely connected subgraph in a protein-protein...
On the hydrodynamic stability of two-dimensional parallel uniform shearing motion of viscous fluid.
Thesis (Ph. D.)--Harvard University, 1950.
Defective Acidification in Human Breast Tumor Cells and Implications for Chemotherapy
Altan, Nihal, Chen, Yu, Schindler, Melvin, Simon, Sanford M.
Multidrug resistance (MDR) is a significant problem in the treatment of cancer. Chemotherapeutic drugs distribute through the cyto- and nucleoplasm of drug-sensitive cells but are excluded from the...
Cet article propose une evaluation de la croissance de la productivite globale des facteurs (PGF) dans l'industrie manufacturiere chinoise et examine l'impact de l'investissement direct etranger sur...
Yu Chen, Thomas Cosimano, Alex Himonas
Analyticity, Asset pricing, Habits, G12, G13, C63, D51,
Solving Asset Pricing Models when the Price-Dividend Function Is Analytic
Ovidiu L. Calin, Yu Chen, Thomas F. Cosimano, Alex A. Himonas
We present a new method for solving asset pricing models, which yields an analytic price-dividend function of one state variable. To illustrate our method we give a detailed analysis of Abel's asset...
In Situ Biochemical Demonstration That P-Glycoprotein Is a Drug Efflux Pump with Broad Specificity
While P-glycoprotein (Pgp) is the most studied protein involved in resistance to anti-cancer drugs, its mechanism of action is still under debate. Studies of Pgp have used cell lines selected with...
Zablotska, Lydia B., Chen, Yu, Graziano, Joseph H., Parvez, Faruque, Van Geen, Alexander, Howe, Geoffrey R., ...
The surface concentrations and concentration depth profiles to the (110) surface of an Au75Pd25 alloy is studied by modified analytical embedded atom method (MAEAM) with the Monte Carlo simulations....
Symbiotic gut microbes modulate human metabolic phenotypes
Li, Min, Wang, Baohong, Zhang, Menghui, Rantalainen, Mattias, Wang, Shengyue, Zhou, Haokui, ...
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in disease...
Politique commerciale et croissance de la PGF : le cas des provinces chinoises
This paper measures the evolution of total factor productivity (TFP) and its components in Chinese provinces for the period of 1992-99. It shows that during this period, TFP, efficiency and...
Wage Differentials and Ownership Structure in Chinese Enterprises
Martin FOURNIER, Sylvie DEMURGER, Yu CHEN
This paper analyses the determinants of wage differentials among different ownership enterprises in urban China in 1955,using an extended version of Oaxaca-Blinder decomposition methods. We find...
Wage Differentials and Ownership Structure in Chinese Enterprises
Yu CHEN, Sylvie DEMURGER, Martin FOURNIER
This paper analyses the determinants of wage differentials among different ownership enterprises in urban China in 1955,using an extended version of Oaxaca-Blinder decomposition methods. We find...
Martine AUDIBERT, Jacky MATHONNAT, Yu CHEN
During the last decades, China has achieved some remarkable results in improving the health status of its population. Since the end of the seventies, it has engaged in a process of large reforms in...
Cited2 is required for normal hematopoiesis in the murine fetal liver
Chen, Yu, Haviernik, Peter, Bunting, Kevin D., Yang, Yu-Chung
Cited2 (cAMP-responsive elementbinding protein [CBP]/p300-interacting transactivators with glutamic acid [E] and aspartic acid [D]–rich tail 2) is a newly identified transcriptional modulator....
Cited2, a coactivator of HNF4α, is essential for liver development
Qu, Xiaoling, Lam, Eric, Doughman, Yong-Qiu, Chen, Yu, Chou, Yu-Ting, Lam, Minh, ...
The transcriptional modulator Cited2 is induced by various biological stimuli including hypoxia, cytokines, growth factors, lipopolysaccharide (LPS) and flow shear. In this study, we report that...
Cell-free selection of RNA-binding proteins using in vitro compartmentalization
Chen, Yu, Mandic, Jana, Varani, Gabriele
RNA-binding proteins (RBPs) perform many essential functions in the post-transcriptional control of gene expression. If we were able to engineer RBPs with new specificity, it would also become...
The Dynamics of Public Opinion in Complex Networks
This paper studies the problem of public opinion formation and concentrates on the interplays among three factors: individual attributes, environmental influences and information flow. We present a...
Let {Xk,k=1,2,...} be a sequence of negatively dependent random variables with common distribution F and finite expectation [mu]. Under the assumption that the tail probability is consistently...
Finite time ruin probability with heavy-tailed insurance and financial risks
This paper studies the probability of ruin within a finite time for a discrete-time model, in which the insurance risk is assumed to be heavy tailed. A precise asymptotic estimate for the finite-time...
Opening-up or institutional development? Evidence from China
'Trade fundamentalists' and 'institutionalists' disagree about whether openness or institutions are more important for economic growth. This paper would like to propose a new perspective: openness...
Analytic solving of asset pricing models: The by force of habit case
Chen, Yu, Cosimano, Thomas F., Himonas, Alex A.
Analytic methods for solving asset pricing models are developed to solve asset pricing models. Campbell and Cochrane's [1999. By force of habit, a consumption-based explanation of aggregate stock...
Multi-Agent Transport Simulations and Economic Evaluation
Kai Nagel, Dominik Grether, Ulrike Beuck, Yu Chen, Marcel Rieser, Kay W. Axhausen
Tolls are frequently discussed policies to reduce traffic in cities. However, road pricing measures are seldom implemented due to high investments and unpopularity. Transportation planning tools can...
Dietary Intake of Methionine, Cysteine, and Protein and Urinary Arsenic Excretion in Bangladesh
Heck, Julia E., Nieves, Jeri W., Chen, Yu, Parvez, Faruque, Brandt-Rauf, Paul W., Graziano, Joseph H., ...
Xu, Chang, Houck, John R., Fan, Wenhong, Wang, Pei, Chen, Yu, Upton, Melissa, ...
Laser capture microdissection (LCM) is used extensively for genome and transcriptome profiling. Traditionally, however, DNA and RNA are purified from separate populations of LCM-harvested cells,...
Functional stoichiometry of the unitary calcium-release-activated calcium channel
Ji, Wei, Xu, Pingyong, Li, Zhengzheng, Lu, Jingze, Liu, Lin, Zhan, Yi, ...
Two proteins, STIM1 in the endoplasmic reticulum and Orai1 in the plasma membrane, are required for the activation of Ca2+ release-activated Ca2+ (CRAC) channels at the cell surface. How these...
Jiang, Li, Fan, Junmei, Bai, Li, Wang, Yan, Chen, Yu, Yang, Lu, ...
Insulin-stimulated GLUT4 translocation to the plasma membrane constitutes a key process for blood glucose control. However, convenient and robust assays to monitor this dynamic process in real time...
What do we need besides trade?
Trade has been shown by many authors to have strong positive impact on productivity. However, we also see some others being more reserved about such an impact. This study intends to investigate...
Molecular mechanisms of calcium-triggered exocytosis /
Submitted to the Program in Neurosciences and the Committee on Graduate Studies of Stanford University.
Liu, Ting-Ting, Lin, You-Hsuan, Hung, Chia-Sui, Liu, Tian-Jiun, Chen, Yu, Huang, Yung-Ching, ...
Rapid and accurate diagnosis for pathogens and their antibiotic susceptibility is critical for controlling bacterial infections. Conventional methods for determining bacterium's sensitivity to...
Socioeconomic Status and Risk for Arsenic-Related Skin Lesions in Bangladesh
Argos, Maria, Parvez, Faruque, Chen, Yu, Momotaj, Hassina, Howe, Geoffrey R., ...
Objectives. Arsenic contamination of groundwater is a severe public health crisis in Bangladesh, where the population is exposed to arsenic in drinking water through tube wells used for groundwater...
This research develops a multilevel and multifaceted perspective on art consumption behavior by separating consumption modes from the consumption products (artworks), by comparing possession...
Functional polymorphism of the NFKB1 gene promoter is related to the risk of dilated cardiomyopathy
Zhou, Bin, Rao, Li, Peng, Ying, Wang, Yanyun, Li, Yi, Gao, Linbo, ...
Qiang, Ya-Wei, Chen, Yu, Stephens, Owen, Brown, Nathan, Chen, Bangzheng, Epstein, Joshua, ...
Multiple myeloma (MM) is characterized by osteolytic bone lesions (OBL) that arise as a consequence of osteoblast inactivation and osteoclast activation adjacent to tumor foci within bone. Wnt...
GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation
Chen, Yu, Deng, Yongqiang, Zhang, Jinzhong, Yang, Lu, Xie, Xiangyang, Xu, Tao
Insulin stimulates GLUT4 (glucose transporter 4) translocation in adipocytes and muscles. An emerging picture is that Rab10 could bridge the gap between the insulin signalling cascade and GLUT4...
Low-Dose Growth Hormone is Cardioprotective in Uremia
Rabkin, Ralph, Awwad, Ibrahim, Chen, Yu, Ashley, Euan A., Sun, Difei, Sood, Sumita, ...
Growth hormone (GH) is required to maintain normal cardiac structure and function and has a positive effect on cardiac remodeling in experimental and possibly human disease. Cardiac resistance to GH...
Chen, Yu, Cai, Hui, Pan, Ji'an, Xiang, Nian, Tien, Po, Ahola, Tero, ...
The N7-methylguanosine (m7G) cap is the defining structural feature of eukaryotic mRNAs. Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to...
Corriden, Ross, Chen, Yu, Inoue, Yoshiaki, Beldi, Guido, Robson, Simon C., Insel, Paul A., ...
Polymorphonuclear neutrophils release ATP in response to stimulation by chemoattractants, such as the peptide N-formyl-methionyl-leucyl-phenylalanine. Released ATP and the hydrolytic product...