Yuanyi Feng

Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination (2008)

Pawlisz, Ashley S., Mutch, Christopher, Wynshaw-Boris, Anthony, Chenn, Anjen, Walsh, Christopher A., Feng, Yuanyi

Neurons in the cerebral cortex originate predominantly from asymmetrical divisions of polarized radial glial or neuroepithelial cells. Fate control of neural progenitors through regulating cell...

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact (2002)

Sheen, Volney L., Feng, Yuanyi, Graham, Donna, Takafuta, Toshiro, Shapiro, Sandor S., Walsh, Christopher A.

Mutations in the X-linked gene Filamin A (FLNA) lead to the human neurological disorder, periventricular heterotopia (PH). Although PH is characterized by a failure in neuronal migration into the...

Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway

Soukoulis, Victor, Reddy, Samyukta, Pooley, Ryan D., Feng, Yuanyi, Walsh, Christopher A., Bader, David M.

LIS1 and nuclear distribution gene E (NudE) are partner proteins in a conserved pathway regulating the function of dynein and microtubules. Here, we present data that cytoplasmic LEK1 (cytLEK1), a...

Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway

Soukoulis, Victor, Reddy, Samyukta, Pooley, Ryan D., Feng, Yuanyi, Walsh, Christopher A., Bader, David M.

LIS1 and nuclear distribution gene E (NudE) are partner proteins in a conserved pathway regulating the function of dynein and microtubules. Here, we present data that cytoplasmic LEK1 (cytLEK1), a...

Filamin A (FLNA) is required for cell–cell contact in vascular development and cardiac morphogenesis

Feng, Yuanyi, Chen, Ming Hui, Moskowitz, Ivan P., Mendonza, Ashley M., Vidali, Luis, Nakamura, Fumihiko, ...

Mutations in the human Filamin A (FLNA) gene disrupt neuronal migration to the cerebral cortex and cause cardiovascular defects. Complete loss of Flna in mice results in embryonic lethality with...

Lis1–Nde1-dependent neuronal fate control determines cerebral cortical size and lamination

Pawlisz, Ashley S., Mutch, Christopher, Wynshaw-Boris, Anthony, Chenn, Anjen, Walsh, Christopher A., Feng, Yuanyi

Neurons in the cerebral cortex originate predominantly from asymmetrical divisions of polarized radial glial or neuroepithelial cells. Fate control of neural progenitors through regulating cell...