Yue Huang

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells (2009)

Wang, Wei, Bradley, Allan, Huang, Yue

Cultured mouse or human embryonic stem (ES) cells provide access to all of the genes required to elaborate the fundamental components and physiological systems of a mammalian cell. Chemical or...

Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice (2009)

Zhuo, Ming-Lei, Huang, Yue, Chen, Jing-Zhou, Sun, Li-Hong, Yang, Rui-Feng, Chen, Hou-Zao, ...

Aims Hypertension is one of the major risk factors for cardiovascular diseases. Endothelial cells (ECs) exert important functions in the regulation of blood pressure. A novel gene, IC53, as an...

Caractérisation de bâtiments par interférométrie SAR polarimétrique multi-images utilisant une méthode d'analyse spectrale adaptative (2009)

YUE HUANG, FERRO-FAMIL, Laurent

Les techniques de l'interférométrie SAR polarimétrique multi-images (multi-bases) notée MB-PollnSAR, sont appliquées dans l'analyse des zones urbaines pour estimer des hauteurs des diffuseurs,...

SUMMARY (2008)

Gregg D. Simonson, Ra C. Vincent, Kevin J. Roberg, Yue Huang, Victoria Iwanij

cloning and characterization of a novel liver-specific transport protein

Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin (2008)

Huang, Yue-Jin, Lundy, Paul M, Lazaris, Anthoula, Huang, Yue, Baldassarre, Hernan, Wang, Bin, ...

Abstract Background Human butyrylcholinesterase (huBChE) has been shown to be an effective antidote against multiple LD 50 of organophosphorus compounds. A prerequisite for such use of huBChE is a...

social links: Integrating social networks with internet routing (2008)

Lerone Banks, Shaozhi Ye, Yue Huang, S. Felix Wu

Internet based communication systems appear in many forms from email to Instant Messenger and chat services to Voice over IP (VoIP). Common weaknesses of these current communication systems include...

The prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease. (2007)

Huang, Yue, Halliday, Glenda M., Vandebona, Himesha, Mellick, George, Mastaglia, Frank, Stevens, Julia, ...

Abstract: We determined the prevalence of two common leucine-rich repeat kinase 2 (LRRK2) gene mutations in Australian patients with Parkinson's disease (PD). Of 830 affected patients, eight were...

The prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease. (2007)

Huang, Yue, Halliday, Glenda M., Vandebona, Himesha, Mellick, George, Mastaglia, Frank, Stevens, Julia, ...

Abstract: We determined the prevalence of two common leucine-rich repeat kinase 2 (LRRK2) gene mutations in Australian patients with Parkinson's disease (PD). Of 830 affected patients, eight were...

The prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease. (2007)

Huang, Yue, Halliday, Glenda M., Vandebona, Himesha, Mellick, George, Mastaglia, Frank, Stevens, Julia, ...

Abstract: We determined the prevalence of two common leucine-rich repeat kinase 2 (LRRK2) gene mutations in Australian patients with Parkinson's disease (PD). Of 830 affected patients, eight were...

Role of feed protocol in achieving chaotic mixing of highly filled flow systems during filling the empty cavity (2006)

Huang, Yue

Chaotic mixing of highly filled viscous fluids is desired but hardly achieved in the electronic packaging industries. The demand for high reliability found in electronic package attracts more and...

Role of feed protocol in achieving chaotic mixing of highly filled flow systems during filling the empty cavity (2006)

Huang, Yue

Chaotic mixing of highly filled viscous fluids is desired but hardly achieved in the electronic packaging industries. The demand for high reliability found in electronic package attracts more and...

Rapid and sensitive dot-matrix methods for genome analysis (2004)

Huang, Yue, Zhang, Ling

Motivation: Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these...

Rapid and sensitive dot-matrix methods for genome analysis (2004)

Huang, Yue, Zhang, Ling

Motivation: Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these...

Rapid and sensitive dot-matrix methods for genome analysis (2004)

Huang, Yue, Zhang, Ling

Motivation: Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these...

Rapid and sensitive dot-matrix methods for genome analysis (2004)

Huang, Yue, Zhang, Ling

Motivation: Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these...

Rapid and sensitive dot-matrix methods for genome analysis (2004)

Huang, Yue, Zhang, Ling

Motivation: Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these...

Intelligent query answering by knowledge discovery techniques (1996)

Jiawei Han, Yue Huang, Nick Cercone, Yongjian Fu

Knowledge discovery facilitates querying database knowledge and intelligent query answering in database systems. In this paper, we investigate the application of discovered knowledge, concept...

Intelligent Query Answering by Knowledge Discovery Techniques (1995)

Jiawei Han, Yue Huang, Nick Cercone

Knowledge discovery in databases facilitates querying database knowledge, cooperative query answering and semantic query optimization in database systems. In this paper, we investigate the...

Intelligent Query Answering by Knowledge Discovery Techniques (1995)

Jiawei Han, Yue Huang, Nick Cercone, Yongjian Fu

Knowledge discovery facilitates querying database knowledge and intelligent query answering in database systems. In this paper, we investigate the application of discovered knowledge, concept...

Discovery of Data Evolution Regularities in Large Databases (1994)

Jiawei Han, Ong Cai, Nick Cercone, Yue Huang

. A large volume of concrete data may change over time in a database. It is important to catch the general trend of such changes and find data evolution (changing) regularities in databases in many...

Sugar maple bark extractives chemistry / (1990)

Huang, Yue.

Thesis (M.S.)--University of Washington, 1990.

The expression of human α-like globin genes in transgenic mice mediated by bacterial artificial chromosome

Feng, Dong-Xiao, Liu, De-Pei, Huang, Yue, Wu, Lin, Li, Tie-Chang, Wu, Min, ...

After screening a bacterial artificial chromosome of human genomic DNA library with human HS-40, ζ-, α-, and θ-globin probes, a 110-kb clone bearing the whole human α-globin gene cluster was...

The Role of Pr55gag in the Annealing of tRNA3Lys to Human Immunodeficiency Virus Type 1 Genomic RNA

Cen, Shan, Huang, Yue, Khorchid, Ahmad, Darlix, Jean-Luc, Wainberg, Mark A., Kleiman, Lawrence

During human immunodeficiency virus type 1 (HIV-1) assembly, the primer tRNA for the reverse transcriptase-catalyzed synthesis of minus-strand strong-stop cDNA, tRNA3Lys, is selectively packaged into...

The Role of Nucleocapsid and U5 Stem/A-Rich Loop Sequences in tRNA3Lys Genomic Placement and Initiation of Reverse Transcription in Human Immunodeficiency Virus Type 1

Huang, Yue, Khorchid, Ahmad, Gabor, Juliana, Wang, Jing, Li, Xuguang, Darlix, Jean-Luc, ...

We have studied the effect of mutations in the human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) sequence on tRNA3Lys genomic placement, i.e., the in vivo placement of primer tRNA3Lys on...

Human Immunodeficiency Virus Type 1-Specific Immunity after Genetic Immunization Is Enhanced by Modification of Gag and Pol Expression

Huang, Yue, Kong, Wing-pui, Nabel, Gary J.

Immunity to human immunodeficiency virus virion-like structures or a polyprotein has been examined after DNA immunization with Rev-independent expression vectors. A Gag-Pol fusion protein stimulated...

Elicitation of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Mucosal Compartments of Rhesus Monkeys by Systemic Vaccination

Baig, Jamal, Levy, Daniel B., McKay, Paul F., Schmitz, Joern E., Santra, Sampa, Subbramanian, Ramu A., ...

Since most human immunodeficiency virus (HIV) infections are initiated following mucosal exposure to the virus, the anatomic containment or abortion of an HIV infection is likely to require...

Enhanced Mucosal Immunoglobulin A Response of Intranasal Adenoviral Vector Human Immunodeficiency Virus Vaccine and Localization in the Central Nervous System

Lemiale, Franck, Kong, Wing-pui, Akyürek, Levent M., Ling, Xu, Huang, Yue, Chakrabarti, Bimal K., ...

Replication-defective adenovirus (ADV) vectors represent a promising potential platform for the development of a vaccine for AIDS. Although this vector is typically administered intramuscularly, it...

Immunogenicity of Multiple Gene and Clade Human Immunodeficiency Virus Type 1 DNA Vaccines

Kong, Wing-Pui, Huang, Yue, Yang, Zhi-Yong, Chakrabarti, Bimal K., Moodie, Zoe, Nabel, Gary J.

The ability to elicit an immune response to a spectrum of human immunodeficiency virus type 1 (HIV-1) gene products from divergent strains is a desirable feature of an AIDS vaccine. In this study, we...

Incorporation of Pol into Human Immunodeficiency Virus Type 1 Gag Virus-Like Particles Occurs Independently of the Upstream Gag Domain in Gag-Pol

Cen, Shan, Niu, Meijuan, Saadatmand, Jenan, Guo, Fei, Huang, Yue, Nabel, Gary J., ...

By using particle-associated reverse transcriptase (RT) activity as an assay for Pol incorporation into human immunodeficiency virus type 1 (HIV-1) Gag virus-like particles (VLPs), it has been found...

pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by Dendritic Cell Transfer through DC-SIGN

Yang, Zhi-Yong, Huang, Yue, Ganesh, Lakshmanan, Leung, Kwanyee, Kong, Wing-Pui, Schwartz, Owen, ...

The severe acute respiratory syndrome coronavirus (SARS-CoV) synthesizes several putative viral envelope proteins, including the spike (S), membrane (M), and small envelope (E) glycoproteins....

Heterologous Envelope Immunogens Contribute to AIDS Vaccine Protection in Rhesus Monkeys

Letvin, Norman L., Huang, Yue, Chakrabarti, Bimal K., Xu, Ling, Seaman, Michael S., Beaudry, Kristin, ...

Because a strategy to elicit broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies has not yet been found, the role of an Env immunogen in HIV-1 vaccine candidates remains...

Generation of Synthetic Severe Acute Respiratory Syndrome Coronavirus Pseudoparticles: Implications for Assembly and Vaccine Production

Huang, Yue, Yang, Zhi-yong, Kong, Wing-pui, Nabel, Gary J.

The recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV) contains four structural genes, two replicase-transcriptase open reading frames, and more than five potential genes of...

Neutralizing Antibodies Elicited by Immunization of Monkeys with DNA Plasmids and Recombinant Adenoviral Vectors Expressing Human Immunodeficiency Virus Type 1 Proteins

Mascola, John R., Sambor, Anna, Beaudry, Kristin, Santra, Sampa, Welcher, Brent, Louder, Mark K., ...

Immunization with recombinant serotype 5 adenoviral (rAd5) vectors or a combination of DNA plasmid priming and rAd5 boosting is known to elicit potent immune responses. However, little data exist...

Multiclade Human Immunodeficiency Virus Type 1 Envelope Immunogens Elicit Broad Cellular and Humoral Immunity in Rhesus Monkeys

Seaman, Michael S., Xu, Ling, Beaudry, Kristin, Martin, Kristi L., Beddall, Margaret H., Miura, Ayako, ...

The development of a human immunodeficiency virus type 1 (HIV-1) vaccine that elicits potent cellular and humoral immune responses recognizing divergent strains of HIV-1 will be critical for...

Replication-Defective Adenovirus Serotype 5 Vectors Elicit Durable Cellular and Humoral Immune Responses in Nonhuman Primates

Santra, Sampa, Seaman, Michael S., Xu, Ling, Barouch, Dan H., Lord, Carol I., Lifton, Michelle A., ...

The magnitude and durability of immune responses induced by replication-defective adenovirus serotype 5 (ADV5) vector-based vaccines were evaluated in the simian-human immunodeficiency virus/rhesus...

The expression of human α-like globin genes in transgenic mice mediated by bacterial artificial chromosome

Feng, Dong-Xiao, Liu, De-Pei, Huang, Yue, Wu, Lin, Li, Tie-Chang, Wu, Min, ...

After screening a bacterial artificial chromosome of human genomic DNA library with human HS-40, ζ-, α-, and θ-globin probes, a 110-kb clone bearing the whole human α-globin gene cluster was...

The Role of Pr55gag in the Annealing of tRNA3Lys to Human Immunodeficiency Virus Type 1 Genomic RNA

Cen, Shan, Huang, Yue, Khorchid, Ahmad, Darlix, Jean-Luc, Wainberg, Mark A., Kleiman, Lawrence

During human immunodeficiency virus type 1 (HIV-1) assembly, the primer tRNA for the reverse transcriptase-catalyzed synthesis of minus-strand strong-stop cDNA, tRNA3Lys, is selectively packaged into...

The Role of Nucleocapsid and U5 Stem/A-Rich Loop Sequences in tRNA3Lys Genomic Placement and Initiation of Reverse Transcription in Human Immunodeficiency Virus Type 1

Huang, Yue, Khorchid, Ahmad, Gabor, Juliana, Wang, Jing, Li, Xuguang, Darlix, Jean-Luc, ...

We have studied the effect of mutations in the human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) sequence on tRNA3Lys genomic placement, i.e., the in vivo placement of primer tRNA3Lys on...

Human Immunodeficiency Virus Type 1-Specific Immunity after Genetic Immunization Is Enhanced by Modification of Gag and Pol Expression

Huang, Yue, Kong, Wing-pui, Nabel, Gary J.

Immunity to human immunodeficiency virus virion-like structures or a polyprotein has been examined after DNA immunization with Rev-independent expression vectors. A Gag-Pol fusion protein stimulated...

Elicitation of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Mucosal Compartments of Rhesus Monkeys by Systemic Vaccination

Baig, Jamal, Levy, Daniel B., McKay, Paul F., Schmitz, Joern E., Santra, Sampa, Subbramanian, Ramu A., ...

Since most human immunodeficiency virus (HIV) infections are initiated following mucosal exposure to the virus, the anatomic containment or abortion of an HIV infection is likely to require...

Enhanced Mucosal Immunoglobulin A Response of Intranasal Adenoviral Vector Human Immunodeficiency Virus Vaccine and Localization in the Central Nervous System

Lemiale, Franck, Kong, Wing-pui, Akyürek, Levent M., Ling, Xu, Huang, Yue, Chakrabarti, Bimal K., ...

Replication-defective adenovirus (ADV) vectors represent a promising potential platform for the development of a vaccine for AIDS. Although this vector is typically administered intramuscularly, it...

Immunogenicity of Multiple Gene and Clade Human Immunodeficiency Virus Type 1 DNA Vaccines

Kong, Wing-Pui, Huang, Yue, Yang, Zhi-Yong, Chakrabarti, Bimal K., Moodie, Zoe, Nabel, Gary J.

The ability to elicit an immune response to a spectrum of human immunodeficiency virus type 1 (HIV-1) gene products from divergent strains is a desirable feature of an AIDS vaccine. In this study, we...

Incorporation of Pol into Human Immunodeficiency Virus Type 1 Gag Virus-Like Particles Occurs Independently of the Upstream Gag Domain in Gag-Pol

Cen, Shan, Niu, Meijuan, Saadatmand, Jenan, Guo, Fei, Huang, Yue, Nabel, Gary J., ...

By using particle-associated reverse transcriptase (RT) activity as an assay for Pol incorporation into human immunodeficiency virus type 1 (HIV-1) Gag virus-like particles (VLPs), it has been found...

pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by Dendritic Cell Transfer through DC-SIGN

Yang, Zhi-Yong, Huang, Yue, Ganesh, Lakshmanan, Leung, Kwanyee, Kong, Wing-Pui, Schwartz, Owen, ...

The severe acute respiratory syndrome coronavirus (SARS-CoV) synthesizes several putative viral envelope proteins, including the spike (S), membrane (M), and small envelope (E) glycoproteins....

Heterologous Envelope Immunogens Contribute to AIDS Vaccine Protection in Rhesus Monkeys

Letvin, Norman L., Huang, Yue, Chakrabarti, Bimal K., Xu, Ling, Seaman, Michael S., Beaudry, Kristin, ...

Because a strategy to elicit broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies has not yet been found, the role of an Env immunogen in HIV-1 vaccine candidates remains...

Generation of Synthetic Severe Acute Respiratory Syndrome Coronavirus Pseudoparticles: Implications for Assembly and Vaccine Production

Huang, Yue, Yang, Zhi-yong, Kong, Wing-pui, Nabel, Gary J.

The recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV) contains four structural genes, two replicase-transcriptase open reading frames, and more than five potential genes of...

Neutralizing Antibodies Elicited by Immunization of Monkeys with DNA Plasmids and Recombinant Adenoviral Vectors Expressing Human Immunodeficiency Virus Type 1 Proteins

Mascola, John R., Sambor, Anna, Beaudry, Kristin, Santra, Sampa, Welcher, Brent, Louder, Mark K., ...

Immunization with recombinant serotype 5 adenoviral (rAd5) vectors or a combination of DNA plasmid priming and rAd5 boosting is known to elicit potent immune responses. However, little data exist...

Multiclade Human Immunodeficiency Virus Type 1 Envelope Immunogens Elicit Broad Cellular and Humoral Immunity in Rhesus Monkeys

Seaman, Michael S., Xu, Ling, Beaudry, Kristin, Martin, Kristi L., Beddall, Margaret H., Miura, Ayako, ...

The development of a human immunodeficiency virus type 1 (HIV-1) vaccine that elicits potent cellular and humoral immune responses recognizing divergent strains of HIV-1 will be critical for...

Replication-Defective Adenovirus Serotype 5 Vectors Elicit Durable Cellular and Humoral Immune Responses in Nonhuman Primates

Santra, Sampa, Seaman, Michael S., Xu, Ling, Barouch, Dan H., Lord, Carol I., Lifton, Michelle A., ...

The magnitude and durability of immune responses induced by replication-defective adenovirus serotype 5 (ADV5) vector-based vaccines were evaluated in the simian-human immunodeficiency virus/rhesus...

Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning

Huang, Yue-Jin, Huang, Yue, Baldassarre, Hernan, Wang, Bin, Lazaris, Anthoula, Leduc, Martin, ...

Dangerous organophosphorus (OP) compounds have been used as insecticides in agriculture and in chemical warfare. Because exposure to OP could create a danger for humans in the future,...

Curcumin prevents and reverses murine cardiac hypertrophy

Li, Hong-Liang, Liu, Chen, De Couto, Geoffrey, Ouzounian, Maral, Sun, Mei, Wang, Ai-Bing, ...

Chromatin remodeling, particularly histone acetylation, plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. We hypothesized that curcumin, a natural...

p25α Relocalizes in Oligodendroglia from Myelin to Cytoplasmic Inclusions in Multiple System Atrophy

Song, Yun Ju C., Lundvig, Ditte M.S., Huang, Yue, Gai, Wei Ping, Blumbergs, Peter C., Højrup, Peter, ...

p25α is an oligodendroglial protein that can induce aggregation of α-synuclein and accumulates in oligodendroglial cell bodies containing fibrillized α-synuclein in the neurodegenerative disease...

Estimating Amoxicillin Influx/Efflux in Chinchilla Middle Ear Fluid and Simultaneous Measurement of Antibacterial Effect▿

Huang, Yue, Yang, Zheng, Cartier, Linda, Cheung, Belinda, Sawchuk, Ronald J.

Understanding the transport process and the factors that control the influx/efflux of antibiotics between plasma and middle ear fluid is essential in optimizing the antimicrobial efficacy in the...

A Filovirus-Unique Region of Ebola Virus Nucleoprotein Confers Aberrant Migration and Mediates Its Incorporation into Virions▿

Shi, Wei, Huang, Yue, Sutton-Smith, Mark, Tissot, Berangere, Panico, Maria, Morris, Howard R., ...

The Ebola virus nucleoprotein (NP) is an essential component of the nucleocapsid, required for filovirus particle formation and replication. Together with virion protein 35 (VP35) and VP24, this gene...

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells

Wang, Wei, Bradley, Allan, Huang, Yue

Cultured mouse or human embryonic stem (ES) cells provide access to all of the genes required to elaborate the fundamental components and physiological systems of a mammalian cell. Chemical or...