Yuesheng Jin

Karyotypic heterogeneity and clonal evolution in squamous cell carcinomas of the head and neck. (2002)

Jin, Charlotte, Jin, Yuesheng, Wennerberg, Johan, Akervall, Jan, Dictor, Michael, Mertens, Fredrik

Head and neck squamous cell carcinomas (HNSCC) are often characterized by complex karyotypic changes, and a substantial proportion of the reported tumors have shown intratumor heterogeneity in the...

Chromosomal translocations involving 11q13 contribute to cyclin D1 overexpression in squamous cell carcinoma of the head and neck. (2002)

Akervall, Jan, Borg, Ake, Dictor, Michael, Jin, Charlotte, Jin, Yuesheng, Tanner, Minna, ...

CCND1 amplification results in cyclin D1 overexpression. However, other unidentified genetic mechanisms contribute to enhanced gene expression. In the present study, 32 squamous cell carcinoma of the...

Cyclin D1 amplification in chromosomal band 11q13 is associated with overrepresentation of 3q21-q29 in head and neck carcinomas. (2002)

Jin, Yuesheng, Jin, Charlotte, Wennerberg, Johan, Höglund, Mattias, Mertens, Fredrik

Eight cytogenetically characterized head and neck squamous cell carcinomas (HNSCCs) with CCND1 amplification in the form of a homogeneously staining region (hsr) in 11q13 were studied by COBRA FISH...

Clonal chromosome abnormalities in premalignant lesions of the skin. (2002)

Jin, Yuesheng, Jin, Charlotte, Salemark, Lars, Wennerberg, Johan, Persson, Bertil, Jonsson, Nils

Two lesions, actinic keratosis (AK) and squamous cell carcinoma in situ (CIS), are believed to be precursors of squamous cell carcinoma (SCC) of the skin. These lesions can serve as an excellent...

Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma1

Jin, Yuesheng, Mertens, Fredrik, Kullendorff, Carl-Magnus, Panagopoulos, Ioannis

We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21;q12) which occurred as the sole cytogenetic aberration in short-term cultured cells from an...

Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma1

Jin, Yuesheng, Mertens, Fredrik, Kullendorff, Carl-Magnus, Panagopoulos, Ioannis

We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21;q12) which occurred as the sole cytogenetic aberration in short-term cultured cells from an...