Morphological Change Caused by Loss of the Taxon-Specific Polyalanine Tract in Hoxd-13 (2007)
Anan, Keiiti, Yoshida, Nobuaki, Kataoka, Yuki, Sato, Mitsuharu, Ichise, Hirotake, Nasu, Makoto, ...
Sequence comparison of Hoxd-13 among vertebrates revealed the presence of taxon-specific polyalanine tracts in amniotes. To investigate their function at the organismal level, we replaced the...
Morphological Change Caused by Loss of the Taxon-Specific Polyalanine Tract in Hoxd-13 (2006)
Anan, Keiiti, Yoshida, Nobuaki, Kataoka, Yuki, Sato, Mitsuharu, Ichise, Hirotake, Nasu, Makoto, ...
Sequence comparison of Hoxd-13 among vertebrates revealed the presence of taxon-specific polyalanine tracts in amniotes. To investigate their function at the organismal level, we replaced the...
SH2-B Is Required for Both Male and Female Reproduction
Ohtsuka, Satoshi, Takaki, Satoshi, Iseki, Masanori, Miyoshi, Kanta, Nakagata, Naomi, Kataoka, Yuki, ...
Many growth factors and hormones modulate the reproductive status in mammals. Among these, insulin and insulin-like growth factor I (IGF-I) regulate the development of gonadal tissues. SH2-B has been...
Zinc Finger Protein Sall2 Is Not Essential for Embryonic and Kidney Development
Sato, Akira, Matsumoto, Yuko, Koide, Urara, Kataoka, Yuki, Yoshida, Nobuaki, Yokota, Takashi, ...
SALL/Sall is a mammalian homolog of the Drosophila region-specific homeotic gene spalt (sal), and heterozygous mutations in SALL1 in humans lead to Townes-Brocks syndrome. We earlier reported that...
Mammalian Twisted Gastrulation Is Essential for Skeleto-Lymphogenesis
Nosaka, Tetsuya, Morita, Sumiyo, Kitamura, Hidetomo, Nakajima, Hideaki, Shibata, Fumi, Morikawa, Yoshihiro, ...
Dorsoventral patterning depends on the local concentrations of the morphogens. Twisted gastrulation (TSG) regulates the extracellular availability of a mesoderm inducer, bone morphogenetic protein 4...
Phospholipase Cδ1 is required for skin stem cell lineage commitment
Nakamura, Yoshikazu, Fukami, Kiyoko, Yu, Haiyan, Takenaka, Kei, Kataoka, Yuki, Shirakata, Yuji, ...
Phosphoinositide-specific phospholipase C (PLC) is a key enzyme in phosphoinositide turnover and is involved in a variety of physiological functions. Here we report that PLCδ1-deficient mice...
Takenaka, Kei, Fukami, Kiyoko, Otsuki, Makiko, Nakamura, Yoshikazu, Kataoka, Yuki, Wada, Mika, ...
Phospholipase C (PLC) plays important roles in phosphoinositide turnover by regulating the calcium-protein kinase C signaling pathway. PLC-L2 is a novel PLC-like protein which lacks PLC activity,...
Iseki, Masanori, Kubo, Chiyomi, Kwon, Sang-Mo, Yamaguchi, Akiko, Kataoka, Yuki, Yoshida, Nobuaki, ...
APS (adaptor molecule containing PH and SH2 domains) is an intracellular adaptor protein that forms an adaptor family along with Lnk and SH2-B. While experiments using cultured cell lines have...
Hiratsuka, Sachie, Kataoka, Yuki, Nakao, Kazuki, Nakamura, Kenji, Morikawa, Shunichi, Tanaka, Satoshi, ...
The hemangioblast in the mesoderm gives rise to both angioblasts and hematopoietic stem cells. The movement of hemangioblast precursor cells in the fetal trunk is a critical event in early...
Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice
Sakurai, Yoshiko, Ohgimoto, Kaori, Kataoka, Yuki, Yoshida, Nobuaki, Shibuya, Masabumi
Flk-1 (human counterpart, KDR) tyrosine kinase, which is one of the two VEGF receptors, is crucial for vascular development. Recently, we showed that, among tyrosine residues of KDR, tyrosine...
Urano, Atsushi, Endoh, Masaki, Wada, Tadashi, Morikawa, Yoshihiro, Itoh, Miyuki, Kataoka, Yuki, ...
AF5q31 (also called MCEF) was identified by its involvement in chromosomal translocation with the gene MLL (mixed lineage leukemia), which is associated with infant acute lymphoblastic leukemia....
SH2-B Is Required for Both Male and Female Reproduction
Ohtsuka, Satoshi, Takaki, Satoshi, Iseki, Masanori, Miyoshi, Kanta, Nakagata, Naomi, Kataoka, Yuki, ...
Many growth factors and hormones modulate the reproductive status in mammals. Among these, insulin and insulin-like growth factor I (IGF-I) regulate the development of gonadal tissues. SH2-B has been...
Zinc Finger Protein Sall2 Is Not Essential for Embryonic and Kidney Development
Sato, Akira, Matsumoto, Yuko, Koide, Urara, Kataoka, Yuki, Yoshida, Nobuaki, Yokota, Takashi, ...
SALL/Sall is a mammalian homolog of the Drosophila region-specific homeotic gene spalt (sal), and heterozygous mutations in SALL1 in humans lead to Townes-Brocks syndrome. We earlier reported that...
Mammalian Twisted Gastrulation Is Essential for Skeleto-Lymphogenesis
Nosaka, Tetsuya, Morita, Sumiyo, Kitamura, Hidetomo, Nakajima, Hideaki, Shibata, Fumi, Morikawa, Yoshihiro, ...
Dorsoventral patterning depends on the local concentrations of the morphogens. Twisted gastrulation (TSG) regulates the extracellular availability of a mesoderm inducer, bone morphogenetic protein 4...
Phospholipase Cδ1 is required for skin stem cell lineage commitment
Nakamura, Yoshikazu, Fukami, Kiyoko, Yu, Haiyan, Takenaka, Kei, Kataoka, Yuki, Shirakata, Yuji, ...
Phosphoinositide-specific phospholipase C (PLC) is a key enzyme in phosphoinositide turnover and is involved in a variety of physiological functions. Here we report that PLCδ1-deficient mice...
Takenaka, Kei, Fukami, Kiyoko, Otsuki, Makiko, Nakamura, Yoshikazu, Kataoka, Yuki, Wada, Mika, ...
Phospholipase C (PLC) plays important roles in phosphoinositide turnover by regulating the calcium-protein kinase C signaling pathway. PLC-L2 is a novel PLC-like protein which lacks PLC activity,...
Iseki, Masanori, Kubo, Chiyomi, Kwon, Sang-Mo, Yamaguchi, Akiko, Kataoka, Yuki, Yoshida, Nobuaki, ...
APS (adaptor molecule containing PH and SH2 domains) is an intracellular adaptor protein that forms an adaptor family along with Lnk and SH2-B. While experiments using cultured cell lines have...
Hiratsuka, Sachie, Kataoka, Yuki, Nakao, Kazuki, Nakamura, Kenji, Morikawa, Shunichi, Tanaka, Satoshi, ...
The hemangioblast in the mesoderm gives rise to both angioblasts and hematopoietic stem cells. The movement of hemangioblast precursor cells in the fetal trunk is a critical event in early...
Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice
Sakurai, Yoshiko, Ohgimoto, Kaori, Kataoka, Yuki, Yoshida, Nobuaki, Shibuya, Masabumi
Flk-1 (human counterpart, KDR) tyrosine kinase, which is one of the two VEGF receptors, is crucial for vascular development. Recently, we showed that, among tyrosine residues of KDR, tyrosine...
Urano, Atsushi, Endoh, Masaki, Wada, Tadashi, Morikawa, Yoshihiro, Itoh, Miyuki, Kataoka, Yuki, ...
AF5q31 (also called MCEF) was identified by its involvement in chromosomal translocation with the gene MLL (mixed lineage leukemia), which is associated with infant acute lymphoblastic leukemia....