Potter, Andrew A., Klashinsky, Sandra, Li, Yuling, Frey, Elizabeth, Townsend, Hugh, Rogan, Dragan, ...
Cattle are an important reservoir of Escherichia coli O157:H7 leading to contamination of food and water, and subsequent human disease. This pathogen colonizes its hosts by producing several proteins...
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Includes abstract.
Deng, Wanyin, Li, Yuling, Vallance, Bruce A., Finlay, B. Brett
The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains a significant...
Human Response to Escherichia coli O157:H7 Infection: Antibodies to Secreted Virulence Factors
Li, Yuling, Frey, Elizabeth, Mackenzie, Andrew M. R., Finlay, B. Brett
Vaccination has been proposed for the prevention of disease due to enterohemorrhagic Escherichia coli (EHEC), but the immune response following human infection, including the choice of potential...
Modulation of T-cell responses to alloantigens by TR6/DcR3
Zhang, Jun, Salcedo, Theodora W., Wan, Xiaochun, Ullrich, Stephen, Hu, Bugen, Gregorio, Theresa, ...
TR6 (DcR3) is a new member of the TNF receptor (TNFR) family that lacks a transmembrane domain in its sequence, indicating that it is a secreted molecule. TR6 can bind to FasL and prevent...
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Li, Yuling, Webster-Cyriaque, Jennifer, Tomlinson, Christine C., Yohe, Marielle, Kenney, Shannon
The Epstein-Barr virus (EBV) immediate-early (IE) protein BRLF1 (R) is a transcription factor that induces the lytic form of EBV infection. R activates certain early viral promoters through a direct...
The C-Mer Gene Is Induced by Epstein-Barr Virus Immediate-Early Protein BRLF1
Li, Yuling, Mahajan, Nupam P., Webster-Cyriaque, Jennifer, Bhende, Prasanna, Hong, Gregory K., Earp, H. Shelton, ...
BRLF1 (R) is one of two Epstein-Barr virus (EBV) immediate-early proteins that mediate the switch from the latent to the lytic form of viral replication. In this report, we show that R induces...
Deng, Wanyin, Li, Yuling, Hardwidge, Philip R., Frey, Elizabeth A., Pfuetzner, Richard A., Lee, Sansan, ...
Human enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC), and the mouse pathogen Citrobacter rodentium (CR) belong to the family of attaching and effacing (A/E) bacterial...
Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...
Coombes, Brian K., Coburn, Bryan A., Potter, Andrew A., Gomis, Susantha, Mirakhur, Kuldip, Li, Yuling, ...
We have developed a novel ileal loop model for use in calves to analyze the contribution of Salmonella enterica serovar Typhimurium type III secretion systems to disease processes in vivo. Our model...
Deng, Wanyin, Li, Yuling, Vallance, Bruce A., Finlay, B. Brett
The family of attaching and effacing (A/E) bacterial pathogens, which includes diarrheagenic enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC), remains a significant...
Human Response to Escherichia coli O157:H7 Infection: Antibodies to Secreted Virulence Factors
Li, Yuling, Frey, Elizabeth, Mackenzie, Andrew M. R., Finlay, B. Brett
Vaccination has been proposed for the prevention of disease due to enterohemorrhagic Escherichia coli (EHEC), but the immune response following human infection, including the choice of potential...
Modulation of T-cell responses to alloantigens by TR6/DcR3
Zhang, Jun, Salcedo, Theodora W., Wan, Xiaochun, Ullrich, Stephen, Hu, Bugen, Gregorio, Theresa, ...
TR6 (DcR3) is a new member of the TNF receptor (TNFR) family that lacks a transmembrane domain in its sequence, indicating that it is a secreted molecule. TR6 can bind to FasL and prevent...
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Li, Yuling, Webster-Cyriaque, Jennifer, Tomlinson, Christine C., Yohe, Marielle, Kenney, Shannon
The Epstein-Barr virus (EBV) immediate-early (IE) protein BRLF1 (R) is a transcription factor that induces the lytic form of EBV infection. R activates certain early viral promoters through a direct...
The C-Mer Gene Is Induced by Epstein-Barr Virus Immediate-Early Protein BRLF1
Li, Yuling, Mahajan, Nupam P., Webster-Cyriaque, Jennifer, Bhende, Prasanna, Hong, Gregory K., Earp, H. Shelton, ...
BRLF1 (R) is one of two Epstein-Barr virus (EBV) immediate-early proteins that mediate the switch from the latent to the lytic form of viral replication. In this report, we show that R induces...
Deng, Wanyin, Li, Yuling, Hardwidge, Philip R., Frey, Elizabeth A., Pfuetzner, Richard A., Lee, Sansan, ...
Human enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC), and the mouse pathogen Citrobacter rodentium (CR) belong to the family of attaching and effacing (A/E) bacterial...
Coburn, Bryan, Li, Yuling, Owen, David, Vallance, Bruce A., Finlay, B. Brett
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid-like illness in...
Coombes, Brian K., Coburn, Bryan A., Potter, Andrew A., Gomis, Susantha, Mirakhur, Kuldip, Li, Yuling, ...
We have developed a novel ileal loop model for use in calves to analyze the contribution of Salmonella enterica serovar Typhimurium type III secretion systems to disease processes in vivo. Our model...
Guttman, Julian A., Samji, Fereshte N., Li, Yuling, Vogl, A. Wayne, Finlay, B. Brett
It is widely accepted that tight junctions are altered during infections by attaching and effacing (A/E) pathogens. These disruptions have been demonstrated both in vitro and more recently in vivo....
Patel, Vikram P., Kreider, Brent L., Li, Yuling, Li, Haodong, Leung, Kam, Salcedo, Theodora, ...
Two novel human β-chemokines, Ckβ-8 or myeloid progenitor inhibitory factor 1 (MPIF-1), and Ckβ-6 or MPIF-2, were discovered as part of a large scale cDNA sequencing effort. The MPIF-1 and MPIF-2...
Salmonella enterica Serovar Senftenberg Human Clinical Isolates Lacking SPI-1▿
Hu, Qinghua, Coburn, Bryan, Deng, Wanyin, Li, Yuling, Shi, Xiaolu, Lan, Quanxue, ...
Nontyphoidal Salmonella species cause gastrointestinal disease worldwide. The prevailing theory of Salmonella enteropathogenesis is that bacterial invasion of the intestinal epithelium is essential...
A note on multinomial maximum likelihood estimation under ordered restrictions and the EM algorithm
Yuling Li, Wei Gao, Ning-Zhong Shi
Maximum likelihood estimation, EM algorithm, Ordered restriction,
Sekirov, Inna, Tam, Nicola M., Jogova, Maria, Robertson, Marilyn L., Li, Yuling, Lupp, Claudia, ...
Intestinal microbiota comprises microbial communities that reside in the gastrointestinal tract and are critical to normal host physiology. Understanding the microbiota's role in host response to...