Yvonne Adams

Rational Design of Anticytoadherence Inhibitors for Plasmodium falciparum Based on the Crystal Structure of Human Intercellular Adhesion Molecule 1

Dormeyer, Matthias, Adams, Yvonne, Kramer, Bernd, Chakravorty, Srabasti, Tse, Man Tsuey, Pegoraro, Stefano, ...

Adhesion of Plasmodium falciparum-infected erythrocytes (IE) to host endothelium has been associated with pathology in malaria. Although the interaction with endothelial cells can be complex due to...

Inhibition of Chondroitin-4-Sulfate-Specific Adhesion of Plasmodium falciparum-Infected Erythrocytes by Sulfated Polysaccharides

Andrews, Katherine T., Klatt, Nicole, Adams, Yvonne, Mischnick, Petra, Schwartz-Albiez, Reinhard

Adhesion of Plasmodium falciparum-infected erythrocytes to placental chondroitin 4-sulfate (CSA) has been linked to the severe disease outcome of pregnancy-associated malaria. Soluble polysaccharides...

Inhibition of Plasmodium falciparum Growth In Vitro and Adhesion to Chondroitin-4-Sulfate by the Heparan Sulfate Mimetic PI-88 and Other Sulfated Oligosaccharides

Adams, Yvonne, Freeman, Craig, Schwartz-Albiez, Reinhard, Ferro, Vito, Parish, Christopher R., Andrews, Katherine T.

A panel of sulfated oligosaccharides was tested for antimalarial activity and inhibition of adhesion to the placental malaria receptor chondroitin-4-sulfate (CSA). The heparan sulfate mimetic PI-88,...

Inhibition of Chondroitin-4-Sulfate-Specific Adhesion of Plasmodium falciparum-Infected Erythrocytes by Sulfated Polysaccharides

Andrews, Katherine T., Klatt, Nicole, Adams, Yvonne, Mischnick, Petra, Schwartz-Albiez, Reinhard

Adhesion of Plasmodium falciparum-infected erythrocytes to placental chondroitin 4-sulfate (CSA) has been linked to the severe disease outcome of pregnancy-associated malaria. Soluble polysaccharides...

Rational Design of Anticytoadherence Inhibitors for Plasmodium falciparum Based on the Crystal Structure of Human Intercellular Adhesion Molecule 1

Dormeyer, Matthias, Adams, Yvonne, Kramer, Bernd, Chakravorty, Srabasti, Tse, Man Tsuey, Pegoraro, Stefano, ...

Adhesion of Plasmodium falciparum-infected erythrocytes (IE) to host endothelium has been associated with pathology in malaria. Although the interaction with endothelial cells can be complex due to...

Inhibition of Plasmodium falciparum Growth In Vitro and Adhesion to Chondroitin-4-Sulfate by the Heparan Sulfate Mimetic PI-88 and Other Sulfated Oligosaccharides

Adams, Yvonne, Freeman, Craig, Schwartz-Albiez, Reinhard, Ferro, Vito, Parish, Christopher R., Andrews, Katherine T.

A panel of sulfated oligosaccharides was tested for antimalarial activity and inhibition of adhesion to the placental malaria receptor chondroitin-4-sulfate (CSA). The heparan sulfate mimetic PI-88,...