'Aplysia' Acetylcholine Receptors: Blockade by and Binding of alpha- Bungarotoxin (2005)
Shain, W. G., Greene, L. A., Carpenter, D. O., Sytkowski, A. J., Vogel, Z.
Alpha-Bungarotoxin (alphaBT) is a snake toxin which in vertebrate systems binds with great specificity to acetylcholine (ACh) receptors. The authors have studied the effects of alpha BT on the...
Carpenter,D. O., Greene,L. A., Shain,W. G. , Jr., Vogel,Z.
Binding of 125 I a-bungarotoxin to acetylcholine receptors of a ganglionic homogenate of the marine mollusc Aplysia is blocked by the anticholinesterases eserine and neostigmine. Eserine and...
We have tested the hypothesis that guanine-nucleotide-binding-protein-coupled receptors may be able to interact with each other at a molecular level. To address this question, we have initially...
Nah, S Y, Saya, D, Barg, J, Vogel, Z
Kappa opiate receptor agonists applied to cocultures of spinal cord and dorsal root ganglion neurons have been previously shown to inhibit voltage-dependent Ca2+ influx and adenylate cyclase...
How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor.
Barchan, D, Kachalsky, S, Neumann, D, Vogel, Z, Ovadia, M, Kochva, E, ...
The ligand binding site of the nicotinic acetylcholine receptor (AcChoR) is within a short peptide from the alpha subunit that includes the tandem cysteine residues at positions 192 and 193. To...
Kalcheim, C, Vogel, Z, Duksin, D
The involvement of extracellular matrix components in induction of the aggregation of acetylcholine (AcCho) receptors by factor(s) present in embryonic brain extract was investigated. Embryonic brain...
Acetylcholine Receptors of Muscle Grown In Vitro
Vogel, Z., Sytkowski, A. J., Nirenberg, M. W.
[125I]Monoiodo- and [125I]diiodo-α-bungarotoxin were synthesized and shown to bind specifically to the acetylcholine receptor of cultured embryonic chick- and rat-muscle cells. The pharmacologic...
Christian, C N, Daniels, M P, Sugiyama, H, Vogel, Z, Jacques, L, Nelson, P G
There is an increase in the number of acetylcholine (AcCho) receptor aggregates on striated embryonic mouse myotubules when they are cocultured with clonal neuroblastoma-glioma hybrid cells. Medium...
Wess, J, Nanavati, S, Vogel, Z, Maggio, R
Most G protein-coupled receptors contain a series of highly conserved proline and tryptophan residues within their hydrophobic transmembrane domains (TMD I-VII). To study their potential role in...
Localization of acetylcholine receptors during synaptogenesis in retina.
Nicotinic acetylcholine receptors are synthesized in chick embryo retina before synapses appear. Most of the receptors are found associated with neurites in the inner synaptic layer of the retina;...
Synapse and acetylcholine receptor synthesis by neurons dissociated from retina.
Vogel, Z, Daniels, M P, Nirenberg, M
Neurons dissociated from chick embryo retina and cultured from more than 1 x 10(8) synapses per mg of protein. At least three types of synapses are synthesized which resemble those of the intact...
Development of Acetylcholine Receptor Clusters on Cultured Muscle Cells
Sytkowski, A. J., Vogel, Z., Nirenberg, M. W.
Clusters of acetylcholine receptors were formed in the absence of neurons during the development of cultured chick-embryo skeletal muscle cells. The average concentration of receptors in clusters was...
Di Marzo, V, Melck, D, Orlando, P, Bisogno, T, Zagoory, O, Bifulco, M, ...
Palmitoylethanolamide (PEA) has been shown to act in synergy with anandamide (arachidonoylethanolamide; AEA), an endogenous agonist of cannabinoid receptor type 1 (CB(1)). This synergistic effect was...
We have tested the hypothesis that guanine-nucleotide-binding-protein-coupled receptors may be able to interact with each other at a molecular level. To address this question, we have initially...
Nah, S Y, Saya, D, Barg, J, Vogel, Z
Kappa opiate receptor agonists applied to cocultures of spinal cord and dorsal root ganglion neurons have been previously shown to inhibit voltage-dependent Ca2+ influx and adenylate cyclase...
How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor.
Barchan, D, Kachalsky, S, Neumann, D, Vogel, Z, Ovadia, M, Kochva, E, ...
The ligand binding site of the nicotinic acetylcholine receptor (AcChoR) is within a short peptide from the alpha subunit that includes the tandem cysteine residues at positions 192 and 193. To...
Kalcheim, C, Vogel, Z, Duksin, D
The involvement of extracellular matrix components in induction of the aggregation of acetylcholine (AcCho) receptors by factor(s) present in embryonic brain extract was investigated. Embryonic brain...
Acetylcholine Receptors of Muscle Grown In Vitro
Vogel, Z., Sytkowski, A. J., Nirenberg, M. W.
[125I]Monoiodo- and [125I]diiodo-α-bungarotoxin were synthesized and shown to bind specifically to the acetylcholine receptor of cultured embryonic chick- and rat-muscle cells. The pharmacologic...
Christian, C N, Daniels, M P, Sugiyama, H, Vogel, Z, Jacques, L, Nelson, P G
There is an increase in the number of acetylcholine (AcCho) receptor aggregates on striated embryonic mouse myotubules when they are cocultured with clonal neuroblastoma-glioma hybrid cells. Medium...
Wess, J, Nanavati, S, Vogel, Z, Maggio, R
Most G protein-coupled receptors contain a series of highly conserved proline and tryptophan residues within their hydrophobic transmembrane domains (TMD I-VII). To study their potential role in...
Localization of acetylcholine receptors during synaptogenesis in retina.
Nicotinic acetylcholine receptors are synthesized in chick embryo retina before synapses appear. Most of the receptors are found associated with neurites in the inner synaptic layer of the retina;...
Synapse and acetylcholine receptor synthesis by neurons dissociated from retina.
Vogel, Z, Daniels, M P, Nirenberg, M
Neurons dissociated from chick embryo retina and cultured from more than 1 x 10(8) synapses per mg of protein. At least three types of synapses are synthesized which resemble those of the intact...
Development of Acetylcholine Receptor Clusters on Cultured Muscle Cells
Sytkowski, A. J., Vogel, Z., Nirenberg, M. W.
Clusters of acetylcholine receptors were formed in the absence of neurons during the development of cultured chick-embryo skeletal muscle cells. The average concentration of receptors in clusters was...
Di Marzo, V, Melck, D, Orlando, P, Bisogno, T, Zagoory, O, Bifulco, M, ...
Palmitoylethanolamide (PEA) has been shown to act in synergy with anandamide (arachidonoylethanolamide; AEA), an endogenous agonist of cannabinoid receptor type 1 (CB(1)). This synergistic effect was...