Wang, Li, Tu, Zhidong, Sun, Fengzhu
Abstract Background The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines...
Tu, Zhidong, Argmann, Carmen, Wong, Kenny K., Mitnaul, Lyndon J., Edwards, Stephen, Sach, Iliana C., ...
Insulin resistance is one of the dominant symptoms of type 2 diabetes (T2D). Although the molecular mechanisms leading to this resistance are largely unknown, experimental data support that the...
Tu, Zhidong, Wang, Li, Xu, Min, Zhou, Xianghong, Chen, Ting, Sun, Fengzhu
Abstract Background Several studies have compared various features of heritable disease genes with other so called non-disease genes, but they have yielded some conflicting results. A potential...
An integrative approach for causal gene identification and gene regulatory pathway inference (2006)
Zhidong Tu, Li Wang, Michelle N. Arbeitman, Ting Chen, Fengzhu Sun
doi:10.1093/bioinformatics/btl234
An integrative approach for causal gene identification and gene regulatory pathway inference (2006)
Tu, Zhidong, Wang, Li, Arbeitman, Michelle N., Chen, Ting, Sun, Fengzhu
Motivation: Gene expression variation can often be linked to certain chromosomal regions and are tightly associated with phenotypic variation such as disease conditions. Inferring the causal genes...
Mapping gene ontology to proteins based on protein-protein interaction data (2004)
Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting
Motivation: Gene Ontology Consortium (GO) provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...
Mapping gene ontology to proteins based on protein-protein interaction data (2004)
Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting
Motivation: Gene Ontology (GO) consortium provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...
Mapping gene ontology to proteins based on protein-protein interaction data (2004)
Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting
Motivation: Gene Ontology Consortium (GO) provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...
Further understanding human disease genes by comparing with housekeeping genes and other genes
Tu, Zhidong, Wang, Li, Xu, Min, Zhou, Xianghong, Chen, Ting, Sun, Fengzhu
Network motif identification in stochastic networks
Jiang, Rui, Tu, Zhidong, Chen, Ting, Sun, Fengzhu
Network motifs have been identified in a wide range of networks across many scientific disciplines and are suggested to be the basic building blocks of most complex networks. Nonetheless, many...