Zhang, Zhongzhi, Lin, Yuan, Zhou, Shuigeng, Wang, Zhigang, Guan, Jihong
Various real-life networks of current interest are simultaneously scale-free and modular. Here we study analytically the average distance in a class of deterministically growing scale-free modular...
Hao, Ningning, Zhang, Wei, Wang, Zhigang, Wang, Yupeng, Zhang, Ping
We study a bilayer two-dimension-electron-gas (2DEG) adjacent to a type-II superconductor thin film with a pinned vortex lattice. We find that with increasing interlayer tunneling, the system of half...
Quantum spin Hall effect and spin-charge separation in kagome lattice (2009)
A two-dimensional kagome lattice has been theoretically investigated within a simple tight-binding model, which includes the nearest neighbor hopping term and the intrinsic spin-orbit interaction...
Topological winding properties of spin edge states in Kane-Mele graphene model (2009)
Wang, Zhigang, Hao, Ningning, Zhang, Ping
We study the spin edge states in the quantum spin-Hall (QSH) effect on a single-atomic layer graphene ribbon system with both intrinsic and Rashba spin-orbit couplings. The Harper equation for...
Fang, Cheng, Wang, Zhigang, Li, Shu-Shen, Zhang, Ping
The magnetization of heavy holes in III-V semiconductor quantum wells with Rashba spin-orbit coupling (SOC) in an external perpendicular magnetic field is theoretically studied. We concentrate on the...
Wang, Zhigang, Zhang, Wei, Zhang, Ping
We study the de Haas--van Alphen (dHvA) oscillations in the magnetization of a two-dimensional electron gas (2DEG) under the influence of the edge states and/or the Rashba spin-orbit interaction...
Topological edge states and quantum Hall effect in the Haldane model (2008)
Hao, Ningning, Zhang, Ping, Wang, Zhigang, Zhang, Wei, Wang, Yupeng
We study the topological edge states of the Haldane's graphene model with zigzag/armchair lattice edges. The Harper equation for solving the energies of the edge states is derived. The results show...
Spin Hall effect in the kagome lattice with Rashba spin-orbit interaction (2008)
Liu, Guocai, Zhang, Ping, Wang, Zhigang, Li, Shu-Shen
We study the spin Hall effect in the kagom\'{e} lattice with Rashba spin-orbit coupling. The conserved spin Hall conductance $\sigma_{xy}^{s}$ (see text) and its two components, i.e., the...
Quantum blockade and loop current induced by a single lattice defect in graphene nanoribbons (2008)
Yan, Jie-Yun, Zhang, Ping, Sun, Bo, Lu, Hai-Zhou, Wang, Zhigang, Duan, Suqing, ...
We investigate theoretically the electronic transport properties in narrow graphene ribbons with an adatom-induced defect. It is found that the lowest conductance step of a metallic graphene...
Song, Min, Liu, Li-Jun, Wang, Zhigang, Nanseki, Teruaki, 南石, 晃明
This paper briefly introduces the history, structure and operation of food traceability system in China and then uses consumer survey data to observe consumers’ attitudes to traceability system in...
Wang, Yihua, Zhao, Cuiping, Wang, Zhigang, Wang, Chengwei, Feng, Wenfeng, Huang, Lijin, ...
Abstract Background It has been reported that various types of axonal injury of hypothalamo-neurohypophyseal tract can result in degeneration of the magnocellular neurons (MCNs) in hypothalamus and...
Meta-Evidence of Asymmetric Price Transmission in US Agricultural Markets (2008)
Zheng, Shi, Miller J. Douglas, Wang, Zhigang, Kai, Satoshi, ミラー, J ダグラス, 王, 志剛, ...
In this paper, we examine the evidence of asymmetric price transmission in several important US agricultural markets. We use estimated asymmetric error correction models (ECM) for producer,...
The chiral edge states and the quantized Hall conductance (QHC) in the two-dimensional kagom\'{e} lattice with spin anisotropies included in a general Hund's coupling region are studied. This...
The orbital magnetization and its effects on the two-dimensional kagom\'{e} lattice with spin anisotropies included in the general Hund's coupling region have been theoretically studied. The results...
The composites (iPP/CNTs) made of isotactic polypropylene (iPP) and multi-wall carbon nanotubes (CNTs) were prepared by solution blending. To improve compatibility between CNTs and iPP and to enhance...
1,4-Diphenylbutane-1,4-dione (2008)
The asymmetric unit of the title compound, C16H14O2, contains one half-molecule, located on a twofold rotation axis. In the molecule, the two benzene rings form a dihedral angle of...
We investigate the chiral edge states in the two-dimensional ferromagntic kagom\'{e} lattice with spin anisotropies included. The system is periodic in the $x$ direction but has two edges in the $y$...
Wang, Zhigang, Weng, Yanzhen, Yutaka, Tomoyuki, Fukuda, Susumu, Kai, Satoshi, 豊, 智行, ...
Based on the data collected from a questionnaire survey of 344 food processing enterprises in China, applying simple quantitative analysis method, this paper mainly analyzes the cost and benefit of...
Sun, Bo, Zhang, Ping, Wang, Zhigang, Duan, Suqing, Zhao, Xian-Geng, Ma, Xuchun, ...
We study the atomic oxygen adsorption on Pb(111) surface by using density-functional theory within the generalized gradient approximation and a supercell approach. The atomic and energetic properties...
Orbital magnetization and its effect in antiferromagnets on the distorted fcc lattice (2007)
Wang, Zhigang, Zhang, Ping, Shi, Junren
We study the intrinsic orbital magnetization (OM) in antiferromagnets on the distorted face-centered-cubic lattice. The combined lattice distortion and spin frustration induce nontrivial $k$-space...
Using the microscopic theory of the conserved spin current [Phys. Rev. Lett. \textbf{96}, 076604 (2006)], we investigate the spin Hall effect in the two dimensional electron gas system with a...
Orbital magnetization and its effects in spin-chiral ferromagnetic Kagome lattice (2007)
Recently, Berry phase in the semiclassical dynamical of Bloch electrons has been found to make a correction to the phase-space density of states and a general multi-band formula for...
Theory of conserved spin current and its application to two dimensional hole gas (2007)
Zhang, Ping, Wang, Zhigang, Shi, Junren, Xiao, Di, Niu, Qian
We present a detailed microscopic theory of the conserved spin current which is introduced by us [Phys. Rev. Lett. \textbf{96}, 196602 (2006)] and satisfies the spin continuity equation even for...
Investigation of the formation and energy density of high-current pulsed electron beams (2007)
Daichi, Yoshiaki, Wang, ZHIGANG, Yamazaki, Kazuo, Sano, Sadao
High-current pulsed electron beams (HCPEB) irradiation is a new potential method to polish hard steels and alloys. After HCPEB machining, the performance of machined surface, such as corrosion...
Investigation of the formation and energy density of high-current pulsed electron beams (2007)
Daichi, Yoshiaki, WANG, ZHIGANG, Yamazaki, Kazuo, Sano, Sadao
High-current pulsed electron beams (HCPEB) irradiation is a new potential method to polish hard steels and alloys. After HCPEB machining, the performance of machined surface, such as corrosion...
Tfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeast (2007)
Zhou, Ying, Kou, Haiping, Wang, Zhigang
TFIIH is indispensable for nucleotide excision repair (NER) and RNA polymerase II transcription. Its tenth subunit was recently discovered in yeast as Tfb5. Unlike other TFIIH subunits, Tfb5 is not...
Tfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeast (2007)
Zhou, Ying, Kou, Haiping, Wang, Zhigang
TFIIH is indispensable for nucleotide excision repair (NER) and RNA polymerase II transcription. Its tenth subunit was recently discovered in yeast as Tfb5. Unlike other TFIIH subunits, Tfb5 is not...
Surface finishing of die and tool steels via plasma-based electron beam irradiation (2006)
Yu, Z, WANG, ZHIGANG, Yamazaki, Kazuo, Sano, S
The plasma-based electron beam (PBEB) irradiation with a maximum diameter of 60 mm has been used to smoothen the workpiece surface. After PBEB irradiation, the machined surface roughness is reduced,...
Discovery of a new class of macrocyclic antagonists to the human motilin receptor (2006)
Hoveyda, Hamid R, Peterson, Mark L, Saint-Louis, Carl, Landry, Annick, Vézina, Martin, ...
A novel class of macrocyclic peptidomimetics was identified and optimized as potent antagonists to the human motilin receptor (hMOT-R). Well-defined structure-activity relationships allowed for rapid...
Wang, Zhigang, Ma, Jianlei, Yutaka, Tomoyuki, Fukuda, Susumu, Kai, Satoshi, 王, 志剛, ...
Using data collected from questionnaire survey on traders, applying quantitative analysis method, the study develops a model for determinants of traders’ performance and explores the effect...
Zhao, Bo, Wang, Jillian, Geacintov, Nicholas E., Wang, Zhigang
Benzo[a]pyrene is an important environmental mutagen and carcinogen. Its metabolism in cells yields the mutagenic, key ultimate carcinogen...
Wang, Zhigang, Yutaka, Tomoyuki, Fukuda, Susumu, Kai, Satoshi, 豊, 智行, 福田, 晋, ...
This paper is to estimate the risk level of agricultural income for each household, to analyze the impact of socioeconomic variables on the households' attitudes towards the risk leves, and to...
Department: Chemistry.
Role of DNA polymerase {eta} in the bypass of abasic sites in yeast cells (2004)
Zhao, Bo, Xie, Zhongwen, Shen, Huiyun, Wang, Zhigang
Abasic (AP) sites are major DNA lesions and are highly mutagenic. AP site-induced mutagenesis largely depends on translesion synthesis. We have examined the role of DNA polymerase η (Polη) in...
Roles of Rad23 protein in yeast nucleotide excision repair (2004)
Xie, Zhongwen, Liu, Shuqian, Zhang, Yanbin, Wang, Zhigang
Nucleotide excision repair (NER) removes many different types of DNA lesions. Most NER proteins are indispensable for repair. In contrast, the yeast Rad23 represents a class of accessory NER...
Guo, Dongyu, Xie, Zhongwen, Shen, Huiyun, Zhao, Bo, Wang, Zhigang
Translesion synthesis is an important mechanism in response to unrepaired DNA lesions during replication. The DNA polymerase ζ (Polζ) mutagenesis pathway is a major error‐prone translesion...
朱, 希剛, 王, 志剛, 豊, 智行, 福田, 晋, 甲斐, 諭, Zhu, Xigang, ...
The purpose of this study is to investigate the product structure, technological progress and international competitive power of rice in China, using the statistical materials and field survey. The...
Sentiment and Social Mitosis: Implications of Heider's Balance Theory (2003)
Wang, Zhigang, Thorngate, Warren
Two Monte Carlo simulations were developed to investigate the social consequences of balancing sentiment relations among triads of members of a larger group, when balancing one triad can imbalance...
Wang, Zhigang, Yutaka, Tomoyuki, Fukuda, Susumu, Kai, Satoshi, 豊, 智行, 福田, 晋, ...
Using the data from a survey conducted among consumers in Tianjin City, this paper examines how the individual consumer attributes effects their food safety, a probit model as used to analyze the...
Hemoglobin levels in Qinghai-Tibet: different effects of gender for (2002)
Haining Zhao, Ping Young, Guilan Li, Zhigang Wang, T. Garl, S. A. Kelly, ...
You might find this additional information useful... This article cites 28 articles, 9 of which you can access free at:
Zhang, Yanbin, Wu, Xiaohua, Rechkoblit, Olga, Geacintov, Nicholas E., Taylor, John-Stephen, Wang, Zhigang
REV1 functions in the DNA polymerase &zgr; mutagenesis pathway. To help understand the role of REV1 in lesion bypass, we have examined activities of purified human REV1 opposite various template...
New techniques for statistical quality control / (2001)
Thesis (M. Eng.)--Nanyang Technological University, School of Mechanical and Production Engineering, 2001.
Pol� Tolerance to some degree of unrepaired DNA damage is crucial for cell survival—more specifically, for the sustained functionality of the DNA replication machinery—in the presence of...
Response of human DNA polymerase {{iota}} to DNA lesions (2001)
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Taylor, John-Stephen, Wang, Zhigang
Lesion bypass is an important mechanism to overcome replication blockage by DNA damage. Translesion synthesis requires a DNA polymerase (Pol). Human Pol ι encoded by the RAD30B gene is a recently...
Wu, Xiaohua, Guo, Dongyu, Yuan, Fenghua, Wang, Zhigang
Nucleotide excision repair (NER) removes a variety of DNA lesions. Using a yeast cell-free repair system, we have analyzed the repair synthesis step of NER. NER was proficient in yeast mutant...
Guo, Dongyu, Wu, Xiaohua, Rajpal, Deepak K., Taylor, John-Stephen, Wang, Zhigang
In the yeast Saccharomyces cerevisiae, DNA polymerase &zgr; (Pol&zgr;) is required in a major lesion bypass pathway. To help understand the role of Pol&zgr; in lesion bypass, we have performed in...
Thesis (Ph. D.)--Michigan Technological University, 2000.
The human RAD18 gene product interacts with HHR6A and HHR6B (2000)
Xin, Hua, Lin, Wensheng, Sumanasekera, Wasana, Zhang, Yanbin, Wu, Xiaohua, Wang, Zhigang
During DNA replication, lesion bypass is an important cellular response to unrepaired damage in the genome. In the yeast Saccharomyces cerevisiae, Rad6 and Rad18 are required for both the error-free...
Error-prone lesion bypass by human DNA polymerase {eta} (2000)
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Rechkoblit, Olga, Taylor, John-Stephen, Geacintov, Nicholas E., ...
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase &eegr; (Pol&eegr;), encoded by the Xeroderma pigmentosum variant (XPV) gene, is known...
Error-free and error-prone lesion bypass by human DNA polymerase {kappa} in vitro (2000)
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Wang, Mu, Rechkoblit, Olga, Taylor, John-Stephen, ...
Error-free lesion bypass and error-prone lesion bypass are important cellular responses to DNA damage during replication, both of which require a DNA polymerase (Pol). To identify lesion bypass DNA...
Human DNA polymerase {kappa} synthesizes DNA with extraordinarily low fidelity (2000)
Zhang, Yanbin, Yuan, Fenghua, Xin, Hua, Wu, Xiaohua, Rajpal, Deepak K., Yang, Danzhou, ...
Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase &kgr; (Pol&kgr;) encoded by the DINB1 gene. Our recent studies...
Intramodule Multielement Microsystem (IM2) Bus and Interface Circuit (1998)
This report describes a communication bus for multielement 'smart sensor' microsystems and the architecture for a sensor bus interface circuit. The Intramodule Multielement Microsystem (IM2) Bus...
Growth and trade with product cycles /--by Zhigang Wang. (1997)
Thesis (Ph. D.)--University of Southern California, 1997.
Molecular analysis of the selective loss of HLA-A2 antigen expression by melanoma cells / (1996)
Program in Microbiology and Immunology. Graduate School of Basic Medical Sciences.
Thesis (Ph. D.)--University of Hawaii at Manoa, 1995.
Thesis (Ph. D.)--University of Minnesota, 1994.
A contrastive approach to language transfer in Chinese and English subject structures / (1990)
Typescript.
Sentiment and Social Mitosis: Implications of Heider's Balance Theory
Zhigang Wang, Warren Thorngate
Two Monte Carlo simulations were developed to investigate the social consequences of balancing sentiment relations among triads of members of a larger group, when balancing one triad can imbalance...
Response of human DNA polymerase ι to DNA lesions
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Taylor, John-Stephen, Wang, Zhigang
Lesion bypass is an important mechanism to overcome replication blockage by DNA damage. Translesion synthesis requires a DNA polymerase (Pol). Human Pol ι encoded by the RAD30B gene is a recently...
Guo, Dongyu, Wu, Xiaohua, Rajpal, Deepak K., Taylor, John-Stephen, Wang, Zhigang
In the yeast Saccharomyces cerevisiae, DNA polymerase ζ (Polζ) is required in a major lesion bypass pathway. To help understand the role of Polζ in lesion bypass, we have performed in vitro...
Wu, Xiaohua, Guo, Dongyu, Yuan, Fenghua, Wang, Zhigang
Nucleotide excision repair (NER) removes a variety of DNA lesions. Using a yeast cell-free repair system, we have analyzed the repair synthesis step of NER. NER was proficient in yeast mutant...
Preferential Incorporation of G Opposite Template T by the Low-Fidelity Human DNA Polymerase ι
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Wang, Zhigang
DNA polymerase activity is essential for replication, recombination, repair, and mutagenesis. All DNA polymerases studied so far from any biological source synthesize DNA by the Watson-Crick...
Highly Frequent Frameshift DNA Synthesis by Human DNA Polymerase μ
Zhang, Yanbin, Wu, Xiaohua, Yuan, Fenghua, Xie, Zhongwen, Wang, Zhigang
DNA polymerase μ (Polμ) is a newly identified member of the polymerase X family. The biological function of Polμ is not known, although it has been speculated that human Polμ may be a somatic...
Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion
Zhang, Yanbin, Wu, Xiaohua, Rechkoblit, Olga, Geacintov, Nicholas E., Taylor, John-Stephen, Wang, Zhigang
REV1 functions in the DNA polymerase ζ mutagenesis pathway. To help understand the role of REV1 in lesion bypass, we have examined activities of purified human REV1 opposite various template bases...
The human RAD18 gene product interacts with HHR6A and HHR6B
Xin, Hua, Lin, Wensheng, Sumanasekera, Wasana, Zhang, Yanbin, Wu, Xiaohua, Wang, Zhigang
During DNA replication, lesion bypass is an important cellular response to unrepaired damage in the genome. In the yeast Saccharomyces cerevisiae, Rad6 and Rad18 are required for both the error-free...
Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Wang, Mu, Rechkoblit, Olga, Taylor, John-Stephen, ...
Error-free lesion bypass and error-prone lesion bypass are important cellular responses to DNA damage during replication, both of which require a DNA polymerase (Pol). To identify lesion bypass DNA...
Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity
Zhang, Yanbin, Yuan, Fenghua, Xin, Hua, Wu, Xiaohua, Rajpal, Deepak K., Yang, Danzhou, ...
Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase κ (Polκ) encoded by the DINB1 gene. Our recent studies have...
Error-prone lesion bypass by human DNA polymerase η
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Rechkoblit, Olga, Taylor, John-Stephen, Geacintov, Nicholas E., ...
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase η (Polη), encoded by the Xeroderma pigmentosum variant (XPV) gene, is known for its...
Guo, Dongyu, Xie, Zhongwen, Shen, Huiyun, Zhao, Bo, Wang, Zhigang
Translesion synthesis is an important mechanism in response to unrepaired DNA lesions during replication. The DNA polymerase ζ (Polζ) mutagenesis pathway is a major error-prone translesion...
Role of DNA polymerase η in the bypass of abasic sites in yeast cells
Zhao, Bo, Xie, Zhongwen, Shen, Huiyun, Wang, Zhigang
Abasic (AP) sites are major DNA lesions and are highly mutagenic. AP site-induced mutagenesis largely depends on translesion synthesis. We have examined the role of DNA polymerase η (Polη) in...
Roles of Rad23 protein in yeast nucleotide excision repair
Xie, Zhongwen, Liu, Shuqian, Zhang, Yanbin, Wang, Zhigang
Nucleotide excision repair (NER) removes many different types of DNA lesions. Most NER proteins are indispensable for repair. In contrast, the yeast Rad23 represents a class of accessory NER...
Zhao, Bo, Wang, Jillian, Geacintov, Nicholas E., Wang, Zhigang
Benzo[a]pyrene is an important environmental mutagen and carcinogen. Its metabolism in cells yields the mutagenic, key ultimate carcinogen...
Response of human DNA polymerase ι to DNA lesions
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Taylor, John-Stephen, Wang, Zhigang
Lesion bypass is an important mechanism to overcome replication blockage by DNA damage. Translesion synthesis requires a DNA polymerase (Pol). Human Pol ι encoded by the RAD30B gene is a recently...
Guo, Dongyu, Wu, Xiaohua, Rajpal, Deepak K., Taylor, John-Stephen, Wang, Zhigang
In the yeast Saccharomyces cerevisiae, DNA polymerase ζ (Polζ) is required in a major lesion bypass pathway. To help understand the role of Polζ in lesion bypass, we have performed in vitro...
Wu, Xiaohua, Guo, Dongyu, Yuan, Fenghua, Wang, Zhigang
Nucleotide excision repair (NER) removes a variety of DNA lesions. Using a yeast cell-free repair system, we have analyzed the repair synthesis step of NER. NER was proficient in yeast mutant...
Preferential Incorporation of G Opposite Template T by the Low-Fidelity Human DNA Polymerase ι
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Wang, Zhigang
DNA polymerase activity is essential for replication, recombination, repair, and mutagenesis. All DNA polymerases studied so far from any biological source synthesize DNA by the Watson-Crick...
Highly Frequent Frameshift DNA Synthesis by Human DNA Polymerase μ
Zhang, Yanbin, Wu, Xiaohua, Yuan, Fenghua, Xie, Zhongwen, Wang, Zhigang
DNA polymerase μ (Polμ) is a newly identified member of the polymerase X family. The biological function of Polμ is not known, although it has been speculated that human Polμ may be a somatic...
Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion
Zhang, Yanbin, Wu, Xiaohua, Rechkoblit, Olga, Geacintov, Nicholas E., Taylor, John-Stephen, Wang, Zhigang
REV1 functions in the DNA polymerase ζ mutagenesis pathway. To help understand the role of REV1 in lesion bypass, we have examined activities of purified human REV1 opposite various template bases...
The human RAD18 gene product interacts with HHR6A and HHR6B
Xin, Hua, Lin, Wensheng, Sumanasekera, Wasana, Zhang, Yanbin, Wu, Xiaohua, Wang, Zhigang
During DNA replication, lesion bypass is an important cellular response to unrepaired damage in the genome. In the yeast Saccharomyces cerevisiae, Rad6 and Rad18 are required for both the error-free...
Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Wang, Mu, Rechkoblit, Olga, Taylor, John-Stephen, ...
Error-free lesion bypass and error-prone lesion bypass are important cellular responses to DNA damage during replication, both of which require a DNA polymerase (Pol). To identify lesion bypass DNA...
Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity
Zhang, Yanbin, Yuan, Fenghua, Xin, Hua, Wu, Xiaohua, Rajpal, Deepak K., Yang, Danzhou, ...
Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase κ (Polκ) encoded by the DINB1 gene. Our recent studies have...
Error-prone lesion bypass by human DNA polymerase η
Zhang, Yanbin, Yuan, Fenghua, Wu, Xiaohua, Rechkoblit, Olga, Taylor, John-Stephen, Geacintov, Nicholas E., ...
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase η (Polη), encoded by the Xeroderma pigmentosum variant (XPV) gene, is known for its...
Guo, Dongyu, Xie, Zhongwen, Shen, Huiyun, Zhao, Bo, Wang, Zhigang
Translesion synthesis is an important mechanism in response to unrepaired DNA lesions during replication. The DNA polymerase ζ (Polζ) mutagenesis pathway is a major error-prone translesion...
Role of DNA polymerase η in the bypass of abasic sites in yeast cells
Zhao, Bo, Xie, Zhongwen, Shen, Huiyun, Wang, Zhigang
Abasic (AP) sites are major DNA lesions and are highly mutagenic. AP site-induced mutagenesis largely depends on translesion synthesis. We have examined the role of DNA polymerase η (Polη) in...
Roles of Rad23 protein in yeast nucleotide excision repair
Xie, Zhongwen, Liu, Shuqian, Zhang, Yanbin, Wang, Zhigang
Nucleotide excision repair (NER) removes many different types of DNA lesions. Most NER proteins are indispensable for repair. In contrast, the yeast Rad23 represents a class of accessory NER...
Zhao, Bo, Wang, Jillian, Geacintov, Nicholas E., Wang, Zhigang
Benzo[a]pyrene is an important environmental mutagen and carcinogen. Its metabolism in cells yields the mutagenic, key ultimate carcinogen...
Tfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeast
Zhou, Ying, Kou, Haiping, Wang, Zhigang
TFIIH is indispensable for nucleotide excision repair (NER) and RNA polymerase II transcription. Its tenth subunit was recently discovered in yeast as Tfb5. Unlike other TFIIH subunits, Tfb5 is not...
Synthetic analogs of green tea polyphenols as proteasome inhibitors.
Smith, David M., Wang, Zhigang, Kazi, Aslamuzzaman, Li, Lian-Hai, Chan, Tak-Hang, Dou, Q. Ping
BACKGROUND: Animal, epidemiological and clinical studies have demonstrated the anti-tumor activity of pharmacological proteasome inhibitors and the cancer-preventive effects of green tea consumption....
Wang, Zhigang, Marincola, Francesco M., Rivoltini, Licia, Parmiani, Giorgio, Ferrone, Soldano
Histocompatibility leukocyte antigen (HLA)-A2 is used as a restricting element to present several melanoma-associated antigen (MAA)-derived peptides to cytotoxic T lymphocytes (CTLs). HLA-A2 antigen...
Structure-guided inhibitor design for human FAAH by interspecies active site conversion
Mileni, Mauro, Johnson, Douglas S., Wang, Zhigang, Everdeen, Daniel S., Liimatta, Marya, Pabst, Brandon, ...
The integral membrane enzyme fatty acid amide hydrolase (FAAH) hydrolyzes the endocannabinoid anandamide and related amidated signaling lipids. Genetic or pharmacological inactivation of FAAH...
Kou, Haiping, Zhou, Ying, Gorospe, R. M. Charlotte, Wang, Zhigang
Nucleotide excision repair (NER) is a major cellular defense mechanism against DNA damage. We have investigated the role of Mms19 in NER in the yeast Saccharomyces cerevisiae. NER was deficient in...
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
Shachar, Sigal, Ziv, Omer, Avkin, Sharon, Adar, Sheera, Wittschieben, John, Reißner, Thomas, ...
Correction to: The EMBO Journal (2009) 28, 383–393. doi:10.1038/emboj.2008.281
A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore
Miller, J. Richard, Dunham, Steve, Mochalkin, Igor, Banotai, Craig, Bowman, Matthew, Buist, Susan, ...
As the need for novel antibiotic classes to combat bacterial drug resistance increases, the paucity of leads resulting from target-based antibacterial screening of pharmaceutical compound libraries...
Zhigang Wang, Huina Yuan, Fred Gale
Implementation of a hazard analysis critical control point (HACCP) system by a Chinese poultry processing company required significant initial investments and greater monthly operation costs,...